Sort by Popularity - Most Popular Movies and TV Shows tagged with keyword "disease"

51. Cabin Fever (2002)

R | 93 min | Horror

Five college graduates rent a cabin in the woods and begin to fall victim to a horrifying flesh-eating virus, which attracts the unwanted attention of the homicidal locals.

Director: Eli Roth | Stars: Jordan Ladd, Rider Strong, James DeBello, Cerina Vincent

Votes: 83,894 | Gross: $21.16M

52. Exam (2009)

Not Rated | 101 min | Crime, Mystery, Thriller

Eight candidates for a highly desirable corporate job are locked together in an exam room and given a final test with just one seemingly simple question. However, it doesn't take long for confusion to ensue and tensions to unravel.

Director: Stuart Hazeldine | Stars: Adar Beck, Gemma Chan, Nathalie Cox, John Lloyd Fillingham

Votes: 125,871

53. Doomsday (I) (2008)

R | 105 min | Action, Sci-Fi, Thriller

A futuristic action thriller where a team of people work to prevent a disaster threatening the future of the human race.

Director: Neil Marshall | Stars: Rhona Mitra, Bob Hoskins, Alexander Siddig, Caryn Peterson

Votes: 80,030 | Gross: $10.96M

54. Night of the Living Dead (1968)

Not Rated | 96 min | Horror, Thriller

A ragtag group of Pennsylvanians barricade themselves in an old farmhouse to remain safe from a horde of flesh-eating ghouls that are ravaging the Northeast of the United States.

Director: George A. Romero | Stars: Duane Jones, Judith O'Dea, Karl Hardman, Marilyn Eastman

Votes: 139,530 | Gross: $0.09M

55. See You on Venus (2023)

94 min | Drama, Romance

An 18 year-old orphaned girl wants to travel to Europe to track down her biological mother, so when she meets a kind-hearted young man reeling from the guilt of a fatal accident, she convinces him to accompany her on the journey.

Director: Joaquín Llamas | Stars: Virginia Gardner, Alex Aiono, Rob Estes, Eowyn Nyby Krieger

Votes: 3,486

56. The Crazies (2010)

R | 101 min | Horror

After a strange and insecure plane crash, an unusual toxic virus enters a quaint farming town. A young couple are quarantined, but they fight for survival along with help from a couple of people.

Director: Breck Eisner | Stars: Radha Mitchell, Timothy Olyphant, Danielle Panabaker, Joe Anderson

Votes: 129,231 | Gross: $39.12M

57. Æon Flux (2005)

PG-13 | 93 min | Action, Adventure, Sci-Fi

Æon Flux is a mysterious assassin working for the Monicans, a group of rebels trying to overthrow the government. When she is sent on a mission to kill the Chairman, a whole new mystery is found.

Director: Karyn Kusama | Stars: Charlize Theron, Frances McDormand, Sophie Okonedo, Marton Csokas

Votes: 132,967 | Gross: $25.87M

58. Resident Evil: Retribution (2012)

R | 95 min | Action, Horror, Sci-Fi

Alice fights alongside a resistance movement to regain her freedom from an Umbrella Corporation testing facility.

Director: Paul W.S. Anderson | Stars: Milla Jovovich, Sienna Guillory, Michelle Rodriguez, Aryana Engineer

Votes: 150,456 | Gross: $42.35M

59. The Division (I)

Action, Sci-Fi, Thriller | Announced

In the near future, a pandemic virus is spread via paper money on Black Friday, decimating New York. A group of civilians, trained to operate in catastrophic times, are activated in an attempt to save who and what remains.

Director: Rawson Marshall Thurber | Stars: Jake Gyllenhaal, Jessica Chastain, McKinley Stamper

60. Mimic (1997)

R | 105 min | Horror, Sci-Fi

Three years ago, entomologist Dr. Susan Tyler genetically created an insect to kill cockroaches carrying a virulent disease. Now, the insects are out to destroy their only predator, mankind.

Director: Guillermo del Toro | Stars: Mira Sorvino, Jeremy Northam, Alexander Goodwin, Giancarlo Giannini

Votes: 55,841 | Gross: $25.48M

61. The Taking of Deborah Logan (2014)

R | 90 min | Horror, Mystery, Thriller

An elderly woman battling Alzheimer's disease agrees to let a film crew document her condition, but what they discover is something far more sinister going on.

Director: Adam Robitel | Stars: Jill Larson, Anne Ramsay, Michelle Ang, Brett Gentile

Votes: 40,509

62. Leviathan (1989)

R | 98 min | Adventure, Horror, Mystery

Perched on the hull of a wrecked Soviet freighter, a team of deep-sea miners led by head oceanographer Steven Beck comes face to face with a mutant creature that's the product of a failed genetic experiment.

Director: George P. Cosmatos | Stars: Peter Weller, Richard Crenna, Amanda Pays, Daniel Stern

Votes: 23,910 | Gross: $15.70M

63. The Last of Us (2013 Video Game)

M | Action, Adventure, Drama

In a hostile, post-pandemic world, Joel and Ellie, brought together by desperate circumstances, must rely on each other to survive a brutal journey across what remains of the United States.

Directors: Neil Druckmann, Bruce Straley | Stars: Troy Baker, Ashley Johnson, Hana Hayes, Jeffrey Pierce

Votes: 76,431

64. Outbreak (1995)

R | 127 min | Action, Drama, Thriller

Army doctors struggle to find a cure for a deadly virus spreading throughout a California town that was brought to America by an African monkey.

Director: Wolfgang Petersen | Stars: Dustin Hoffman, Rene Russo, Morgan Freeman, Kevin Spacey

Votes: 138,096 | Gross: $67.82M

65. Resident Evil: The Final Chapter (2016)

R | 107 min | Action, Horror, Sci-Fi

Alice returns to where the nightmare began: The Hive in Raccoon City, where the Umbrella Corporation is gathering its forces for a final strike against the only remaining survivors of the apocalypse.

Director: Paul W.S. Anderson | Stars: Milla Jovovich, Iain Glen, Ali Larter, Shawn Roberts

Votes: 101,255 | Gross: $26.83M

66. eXistenZ (1999)

R | 97 min | Horror, Mystery, Sci-Fi

A game designer on the run from assassins must play her latest virtual reality creation with a marketing trainee to determine if the game has been damaged.

Director: David Cronenberg | Stars: Jude Law, Jennifer Jason Leigh, Ian Holm, Willem Dafoe

Votes: 107,446 | Gross: $2.84M

67. Lorenzo's Oil (1992)

PG-13 | 129 min | Biography, Drama

Lorenzo Odone, a Virginia 5-year-old, develops a degenerative nerve disease so rare that nobody is working on a cure, so his parents decide to immerse themselves in research and tackle the problem themselves.

Director: George Miller | Stars: Nick Nolte, Susan Sarandon, Peter Ustinov, Kathleen Wilhoite

Votes: 24,140 | Gross: $7.29M

68. The Cure (1995)

PG-13 | 97 min | Adventure, Drama

Erik, a loner, finds a friend in Dexter, an eleven-year-old boy with AIDS. They vow to find a cure for AIDS together and save Dexter's life in an eventful summer.

Director: Peter Horton | Stars: Joseph Mazzello, Brad Renfro, Aeryk Egan, Delphine French

Votes: 10,716 | Gross: $2.57M

69. Eli (I) (2019)

R | 98 min | Drama, Horror, Mystery

A boy receiving treatment for his auto-immune disorder discovers that the house he's living in isn't as safe as he thought.

Director: Ciarán Foy | Stars: Charlie Shotwell, Kelly Reilly, Max Martini, Lili Taylor

Votes: 40,987

70. Balto (1995)

G | 78 min | Animation, Adventure, Drama

An outcast Husky risks his life with other sled dogs to prevent a deadly epidemic from ravaging Nome, Alaska.

Director: Simon Wells | Stars: Kevin Bacon, Bob Hoskins, Bridget Fonda, Jim Cummings

Votes: 48,246 | Gross: $11.35M

71. Dreamcatcher (2003)

R | 134 min | Drama, Horror, Sci-Fi

Friends on a camping trip discover that the town they're vacationing in is being plagued in an unusual fashion by parasitic aliens from outer space.

Director: Lawrence Kasdan | Stars: Morgan Freeman, Thomas Jane, Jason Lee, Damian Lewis

Votes: 96,595 | Gross: $33.72M

72. Rose Red (2002)

PG-13 | 85 min | Horror, Mystery, Thriller

A college professor and a team of psychics investigate mysterious deaths and disappearances at an old abandoned mansion.

Stars: Nancy Travis, Matt Keeslar, Kimberly J. Brown, David Dukes

Votes: 27,098

73. The Omega Man (1971)

PG | 98 min | Action, Drama, Sci-Fi

Dr Robert Neville has developed an experimental vaccine which makes him the only immune survivor of a biological catastrophe. A gang of homicidal mutants blame science for their condition and attempt to kill him.

Director: Boris Sagal | Stars: Charlton Heston, Anthony Zerbe, Rosalind Cash, Paul Koslo

Votes: 34,129 | Gross: $8.72M

74. Osmosis Jones (2001)

PG | 95 min | Animation, Action, Adventure

A policeman white blood cell, with the help of a cold pill, must stop a deadly virus from destroying the human they live in, Frank.

Directors: Bobby Farrelly, Peter Farrelly | Stars: Laurence Fishburne, Chris Rock, David Hyde Pierce, Brandy Norwood

Votes: 38,863 | Gross: $13.60M

75. Night of the Living Dead (1990)

R | 92 min | Horror

When the unburied dead return to life and seek human victims, seven refugees shelter in a house in the Pennsylvanian countryside.

Director: Tom Savini | Stars: Tony Todd, Patricia Tallman, Tom Towles, McKee Anderson

Votes: 45,622 | Gross: $5.84M

76. Arctic Circle (2018– )

TV-MA | 50 min | Crime, Drama, Thriller

A detective and a virologist pursue an unusual investigation that places them on the wrong side of the law.

Stars: Iina Kuustonen, Pihla Viitala, Venla Ronkainen, Mikko Leppilampi

Votes: 2,839

77. Thirst (2009)

R | 134 min | Drama, Fantasy, Horror

Through a failed medical experiment, a priest is stricken with vampirism and is forced to abandon his ascetic ways.

Director: Park Chan-wook | Stars: Song Kang-ho, Kim Ok-bin, Choi Hee-jin, Seo Dong-soo

Votes: 51,522 | Gross: $0.30M

78. Midnight Sun (2018)

PG-13 | 91 min | Drama, Romance

A 17-year-old girl suffers from a condition that prevents her from being out in the sunlight.

Director: Scott Speer | Stars: Bella Thorne, Patrick Schwarzenegger, Rob Riggle, Quinn Shephard

Votes: 36,271 | Gross: $9.56M

79. Cat on a Hot Tin Roof (1958)

Not Rated | 108 min | Drama

Brick is an alcoholic ex-football player who drinks his days away and resists the affections of his wife. A reunion with his terminal father jogs a host of memories and revelations for both father and son.

Director: Richard Brooks | Stars: Elizabeth Taylor, Paul Newman, Burl Ives, Jack Carson

Votes: 53,524 | Gross: $17.57M

80. The Girl with All the Gifts (2016)

R | 111 min | Action, Adventure, Drama

A scientist and a teacher living in a dystopian future embark on a journey of survival with a special young girl named Melanie.

Director: Colm McCarthy | Stars: Sennia Nanua, Fisayo Akinade, Dominique Tipper, Paddy Considine

Votes: 64,597

81. Shivers (1975)

R | 87 min | Horror, Sci-Fi

The residents of a suburban high-rise apartment building are being infected by a strain of parasites that turn them into mindless, sex-crazed fiends out to infect others by the slightest sexual contact.

Director: David Cronenberg | Stars: Paul Hampton, Joe Silver, Lynn Lowry, Allan Kolman

Votes: 23,667

82. The Andromeda Strain (1971)

G | 131 min | Mystery, Sci-Fi, Thriller

Top scientists work feverishly in a secret, state-of-the-art laboratory to discover what killed the citizens of a small town and how the deadly contagion can be stopped.

Director: Robert Wise | Stars: James Olson, Arthur Hill, David Wayne, Kate Reid

Votes: 40,539 | Gross: $3.42M

83. A Prophet (2009)

R | 155 min | Crime, Drama

A delinquent Muslim man struggles to get by in prison until he is taken under the wing of a powerful mob boss. But his gradual rise through the mob's ranks brings him in conflict with his mentor.

Director: Jacques Audiard | Stars: Tahar Rahim, Niels Arestrup, Adel Bencherif, Reda Kateb

Votes: 102,348 | Gross: $2.08M

84. The Bay (II) (2012)

R | 85 min | Horror, Sci-Fi, Thriller

Chaos breaks out in a small Maryland town after an ecological disaster occurs.

Director: Barry Levinson | Stars: Will Rogers, Kristen Connolly, Kether Donohue, Frank Deal

Votes: 29,732 | Gross: $0.03M

85. Phenomenon (1996)

PG | 123 min | Drama, Fantasy, Romance

An ordinary man sees a bright light descend from the sky, and discovers he now has super-intelligence and telekinesis.

Director: Jon Turteltaub | Stars: John Travolta, Kyra Sedgwick, Forest Whitaker, Robert Duvall

Votes: 83,948 | Gross: $104.64M

86. Everything, Everything (2017)

PG-13 | 96 min | Drama, Romance

A teenager who's spent her whole life confined to her home falls for the boy next door.

Director: Stella Meghie | Stars: Amandla Stenberg, Nick Robinson, Anika Noni Rose, Ana de la Reguera

Votes: 42,588 | Gross: $34.00M

87. The Wolfman (2010)

R | 103 min | Drama, Fantasy, Horror

Upon his return to his ancestral homeland, an American man is bitten and subsequently cursed by a werewolf.

Director: Joe Johnston | Stars: Benicio Del Toro, Anthony Hopkins, Emily Blunt, Simon Merrells

Votes: 111,863 | Gross: $61.98M

88. The Darkest Minds (2018)

PG-13 | 104 min | Action, Adventure, Drama

After a disease kills 98% of children, the survivors develop powers and are declared a threat. 16-year-old Ruby, escapes the government facility and joins a group of rebel teenagers ready to fight the government forces out to get them.

Director: Jennifer Yuh Nelson | Stars: Amandla Stenberg, Mandy Moore, Bradley Whitford, Harris Dickinson

Votes: 36,164 | Gross: $12.70M

89. Patient Zero (I) (2018)

R | 93 min | Action, Drama, Horror

After an unprecedented global pandemic turns the majority of humankind into violent "Infected," a man gifted with the ability to speak the Infected's new language leads the last survivors on a hunt for Patient Zero and a cure.

Director: Stefan Ruzowitzky | Stars: Matt Smith, Natalie Dormer, John Bradley, Clive Standen

Votes: 9,990

90. The Normal Heart (2014 TV Movie)

TV-MA | 132 min | Biography, Drama, History

In the early 1980s, the onset of the HIV-AIDS crisis in New York led to an emergence of homosexual activists. With support from the medical community, they try to raise awareness about the disease.

Director: Ryan Murphy | Stars: Mark Ruffalo, Jonathan Groff, Frank De Julio, William DeMeritt

Votes: 37,844

91. Andrei Rublev (1966)

R | 189 min | Biography, Drama, History

The life, times and afflictions of the fifteenth-century Russian iconographer St. Andrei Rublev.

Director: Andrei Tarkovsky | Stars: Anatoliy Solonitsyn, Ivan Lapikov, Nikolay Grinko, Nikolay Sergeev

Votes: 57,186 | Gross: $0.10M

92. In America (2002)

PG-13 | 105 min | Drama

A family of Irish immigrants adjust to life on the mean streets of Hell's Kitchen while also grieving the death of a child.

Director: Jim Sheridan | Stars: Paddy Considine, Samantha Morton, Djimon Hounsou, Sarah Bolger

Votes: 44,320 | Gross: $15.54M

93. Everything Now (2023)

TV-MA | 45 min | Comedy, Drama

Follows Mia Polanco, who is released from hospital after a lengthy battle with anorexia, she is thrust back into the world of sixth form.

Stars: Sophie Wilde, Lauryn Ajufo, Harry Cadby, Noah Thomas

Votes: 3,280

94. Viral (I) (2016)

R | 85 min | Drama, Horror, Sci-Fi

Following the outbreak of a virus that wipes out the majority of the human population, a young woman documents her family's new life in quarantine and tries to protect her infected sister.

Directors: Henry Joost, Ariel Schulman | Stars: Sofia Black-D'Elia, Lio Tipton, Travis Tope, Michael Kelly

Votes: 9,765

95. Dangerous Beauty (1998)

R | 111 min | Biography, Drama, Romance

A Venetian courtesan becomes a hero to her city, but later becomes the target of an inquisition by the Church for witchcraft.

Director: Marshall Herskovitz | Stars: Catherine McCormack, Rufus Sewell, Oliver Platt, Fred Ward

Votes: 19,677 | Gross: $4.53M

96. Love in the Time of Cholera (2007)

R | 139 min | Drama, Romance

Florentino, rejected by the beautiful Fermina at a young age, devotes much of his adult life to carnal affairs as a desperate attempt to heal his broken heart.

Director: Mike Newell | Stars: Javier Bardem, Giovanna Mezzogiorno, Benjamin Bratt, Gina Bernard Forbes

Votes: 24,151 | Gross: $4.61M

97. Blindness (2008)

R | 121 min | Drama, Mystery, Thriller

A city is ravaged by an epidemic of instant white blindness.

Director: Fernando Meirelles | Stars: Julianne Moore, Mark Ruffalo, Gael García Bernal, Yûsuke Iseya

Votes: 75,263 | Gross: $3.07M

98. Cowboy Bebop: The Movie (2001)

TV-14 | 115 min | Animation, Action, Crime

A terrorist explosion releases a deadly virus on the masses, and it's up to the bounty-hunting Bebop crew to catch the cold-blooded culprit.

Directors: Shin'ichirô Watanabe, Mary Elizabeth McGlynn, Tensai Okamura, Hiroyuki Okiura, Yoshiyuki Takei | Stars: Beau Billingslea, Melissa Fahn, Nicholas Guest, Kôichi Yamadera

Votes: 53,344 | Gross: $1.00M

99. Last Holiday (2006)

PG-13 | 112 min | Comedy, Drama, Romance

Upon learning of a terminal illness, a shy woman decides to sell all her possessions and live it up at a posh Central European hotel.

Director: Wayne Wang | Stars: Queen Latifah, LL Cool J, Timothy Hutton, Giancarlo Esposito

Votes: 36,345 | Gross: $38.36M

100. Live Flesh (1997)

R | 103 min | Drama

After leaving jail, Víctor is still in love with Elena, but she's married to the former cop -now basketball player- who became paralysed by a shot from Víctor's gun...

Director: Pedro Almodóvar | Stars: Liberto Rabal, Francesca Neri, Javier Bardem, Ángela Molina

Votes: 33,762 | Gross: $1.54M