Sort by Popularity - Most Popular Movies and TV Shows tagged with keyword "human-experimentation"
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1. Rise of the Planet of the Apes (2011)
PG-13 | 105 min | Action, Drama, Sci-Fi
A substance designed to help the brain repair itself gives advanced intelligence to a chimpanzee who leads an ape uprising.
Director: Rupert Wyatt | Stars: James Franco, Andy Serkis, Freida Pinto, Karin Konoval
Votes: 567,538 | Gross: $176.76M
2. Once Upon a Time (2011–2018)
TV-PG | 60 min | Adventure, Fantasy, Romance
A young woman with a troubled past is drawn to a small town in Maine where fairy tales are to be believed.
Stars: Ginnifer Goodwin, Jennifer Morrison, Lana Parrilla, Robert Carlyle
Votes: 237,442
3. Deadpool (2016)
R | 108 min | Action, Comedy
A wisecracking mercenary gets experimented on and becomes immortal yet hideously scarred, and sets out to track down the man who ruined his looks.
Director: Tim Miller | Stars: Ryan Reynolds, Morena Baccarin, T.J. Miller, Ed Skrein
Votes: 1,129,217 | Gross: $363.07M
4. Shutter Island (2010)
R | 138 min | Drama, Mystery, Thriller
Teddy Daniels and Chuck Aule, two US marshals, are sent to an asylum on a remote island in order to investigate the disappearance of a patient, where Teddy uncovers a shocking truth about the place.
Director: Martin Scorsese | Stars: Leonardo DiCaprio, Emily Mortimer, Mark Ruffalo, Ben Kingsley
Votes: 1,461,604 | Gross: $128.01M
5. A Clockwork Orange (1971)
R | 136 min | Crime, Sci-Fi
In the future, a sadistic gang leader is imprisoned and volunteers for a conduct-aversion experiment, but it doesn't go as planned.
Director: Stanley Kubrick | Stars: Malcolm McDowell, Patrick Magee, Michael Bates, Warren Clarke
Votes: 882,825 | Gross: $6.21M
6. The Guest (I) (2014)
R | 100 min | Action, Mystery, Thriller
A soldier introduces himself to the Peterson family, claiming to be a friend of their son who died in action. After the young man is welcomed into their home, a series of accidental deaths seem to be connected to his presence.
Director: Adam Wingard | Stars: Dan Stevens, Sheila Kelley, Maika Monroe, Joel David Moore
Votes: 107,274 | Gross: $0.32M
7. The Terminal List (2022– )
TV-MA | 55 min | Action, Drama, Thriller
A former Navy SEAL officer investigates why his entire platoon was ambushed during a high-stakes covert mission.
Stars: Chris Pratt, Constance Wu, Taylor Kitsch, Riley Keough
Votes: 107,919
8. Old (2021)
PG-13 | 108 min | Drama, Horror, Mystery
A vacationing family discovers that the secluded beach where they're relaxing for a few hours is somehow causing them to age rapidly, reducing their entire lives into a single day.
Director: M. Night Shyamalan | Stars: Gael García Bernal, Vicky Krieps, Rufus Sewell, Alex Wolff
Votes: 161,783 | Gross: $48.28M
9. The Human Centipede (First Sequence) (2009)
R | 92 min | Horror
A mad scientist kidnaps and mutilates a trio of tourists in order to reassemble them into a human centipede, created by stitching their mouths to each others' rectums.
Director: Tom Six | Stars: Dieter Laser, Winter Williams, Ashlynn Yennie, Akihiro Kitamura
Votes: 87,525 | Gross: $0.18M
10. V for Vendetta (2005)
R | 132 min | Action, Drama, Sci-Fi
In a future British dystopian society, a shadowy freedom fighter, known only by the alias of "V", plots to overthrow the tyrannical government - with the help of a young woman.
Director: James McTeigue | Stars: Hugo Weaving, Natalie Portman, Rupert Graves, Stephen Rea
Votes: 1,181,188 | Gross: $70.51M
11. Maze Runner: The Death Cure (2018)
PG-13 | 143 min | Action, Adventure, Sci-Fi
Young hero Thomas embarks on a mission to find a cure for a deadly disease known as "The Flare".
Director: Wes Ball | Stars: Dylan O'Brien, Ki Hong Lee, Kaya Scodelario, Thomas Brodie-Sangster
Votes: 164,567 | Gross: $58.03M
12. Resident Evil (2002)
R | 100 min | Action, Horror, Sci-Fi
A special military unit fights a powerful, out-of-control supercomputer and hundreds of scientists who have mutated into flesh-eating creatures after a laboratory accident.
Director: Paul W.S. Anderson | Stars: Milla Jovovich, Michelle Rodriguez, Ryan McCluskey, Oscar Pearce
Votes: 289,123 | Gross: $40.12M
13. Cowboys & Aliens (2011)
PG-13 | 119 min | Action, Drama, Sci-Fi
A spaceship arrives in 1873 Arizona to take over the Earth, starting with the Wild West region. All that stands in their way: a posse of cowboys and natives.
Director: Jon Favreau | Stars: Daniel Craig, Harrison Ford, Olivia Wilde, Abigail Spencer
Votes: 232,915 | Gross: $100.24M
14. Dark City (1998)
R | 100 min | Fantasy, Mystery, Sci-Fi
A man struggles with memories of his past, which include a wife he cannot remember and a nightmarish world no one else ever seems to wake up from.
Director: Alex Proyas | Stars: Rufus Sewell, Kiefer Sutherland, Jennifer Connelly, William Hurt
Votes: 212,704 | Gross: $14.38M
15. Alien: Resurrection (1997)
R | 109 min | Action, Horror, Sci-Fi
Two centuries after her death, a powerful human/alien hybrid clone of Ellen Ripley aids a crew of space pirates in stopping the aliens from reaching Earth.
Director: Jean-Pierre Jeunet | Stars: Sigourney Weaver, Winona Ryder, Dominique Pinon, Ron Perlman
Votes: 264,066 | Gross: $47.75M
16. Jacob's Ladder (I) (1990)
R | 113 min | Drama, Horror, Mystery
Mourning his dead child, a haunted Vietnam War veteran attempts to uncover his past while suffering from a severe case of dissociation. To do so, he must decipher reality and life from his own dreams, delusions, and perceptions of death.
Director: Adrian Lyne | Stars: Tim Robbins, Elizabeth Peña, Danny Aiello, Matt Craven
Votes: 118,173 | Gross: $26.12M
17. Resident Evil: Welcome to Raccoon City (2021)
R | 107 min | Action, Horror, Sci-Fi
Set in 1998, this origin story explores the secrets of the mysterious Spencer Mansion and the ill-fated Raccoon City.
Director: Johannes Roberts | Stars: Kaya Scodelario, Robbie Amell, Hannah John-Kamen, Tom Hopper
Votes: 64,414 | Gross: $17.00M
18. The Void (I) (2016)
Not Rated | 90 min | Horror, Mystery, Sci-Fi
Shortly after delivering a patient to an understaffed hospital, a police officer experiences strange and violent occurrences seemingly linked to a group of mysterious hooded figures.
Directors: Jeremy Gillespie, Steven Kostanski | Stars: Aaron Poole, Kenneth Welsh, Ellen Wong, Kathleen Munroe
Votes: 41,821 | Gross: $0.15M
19. Akira (1988)
R | 124 min | Animation, Action, Drama
A secret military project endangers Neo-Tokyo when it turns a biker gang member into a rampaging psychic psychopath who can only be stopped by a teenager, his gang of biker friends and a group of psychics.
Director: Katsuhiro Ôtomo | Stars: Mitsuo Iwata, Nozomu Sasaki, Mami Koyama, Tesshô Genda
Votes: 205,877 | Gross: $0.55M
20. Foe (2023)
R | 110 min | Drama, Romance, Sci-Fi
Hen and Junior farm a secluded piece of land that has been in Junior's family for generations, but their quiet life is thrown into turmoil when an uninvited stranger shows up at their door with a startling proposal.
Director: Garth Davis | Stars: Saoirse Ronan, Paul Mescal, Aaron Pierre, Jordan Chodziesner
Votes: 9,972
21. A Cure for Wellness (2016)
R | 146 min | Drama, Fantasy, Horror
An ambitious young executive is sent to retrieve his company's CEO from an idyllic but mysterious "wellness center" at a remote location in the Swiss Alps, but soon suspects that the spa's treatments are not what they seem.
Director: Gore Verbinski | Stars: Dane DeHaan, Jason Isaacs, Mia Goth, Ivo Nandi
Votes: 109,902 | Gross: $8.11M
22. Superhero Movie (2008)
PG-13 | 75 min | Action, Comedy, Sci-Fi
Orphaned high school student Rick Riker is bitten by a radioactive dragonfly, develops super powers (except for the ability to fly), and becomes a hero.
Director: Craig Mazin | Stars: Drake Bell, Leslie Nielsen, Sara Paxton, Christopher McDonald
Votes: 75,850 | Gross: $26.64M
23. Overlord (2018)
R | 110 min | Action, Horror, Sci-Fi
A small group of American soldiers find horror behind enemy lines on the eve of D-Day.
Director: Julius Avery | Stars: Jovan Adepo, Wyatt Russell, Mathilde Ollivier, Pilou Asbæk
Votes: 106,766 | Gross: $21.70M
24. Resident Evil: Apocalypse (2004)
R | 94 min | Action, Horror, Sci-Fi
Alice wakes up in the Raccoon City hospital after the area has been overrun by zombies, and must now make it out of the city before a nuclear bomb is dropped.
Director: Alexander Witt | Stars: Milla Jovovich, Sienna Guillory, Eric Mabius, Oded Fehr
Votes: 210,302 | Gross: $51.20M
25. Hollow Man (2000)
R | 112 min | Action, Horror, Sci-Fi
A brilliant scientist's discovery renders him invisible, but transforms him into an omnipotent, dangerous megalomaniac.
Director: Paul Verhoeven | Stars: Kevin Bacon, Elisabeth Shue, Josh Brolin, Kim Dickens
Votes: 138,614 | Gross: $73.21M
26. Hanna (2011)
PG-13 | 111 min | Action, Adventure, Drama
A sixteen-year-old girl who was raised by her father to be the perfect assassin is dispatched on a mission across Europe, tracked by a ruthless intelligence agent and her operatives.
Director: Joe Wright | Stars: Saoirse Ronan, Cate Blanchett, Eric Bana, Vicky Krieps
Votes: 207,064 | Gross: $40.26M
27. Enter the Dragon (1973)
R | 102 min | Action, Crime, Thriller
A Shaolin martial artist travels to an island fortress to spy on an opium lord - who is also a former monk from his temple - under the guise of attending a fighting tournament.
Director: Robert Clouse | Stars: Bruce Lee, John Saxon, Jim Kelly, Ahna Capri
Votes: 113,203 | Gross: $25.00M
28. Gyeongseong Creature (2023– )
TV-MA | 60 min | Action, Drama, History
In Spring 1945 in Gyeongseong, during Japanese rule over Korea, two young adults confront a strange creature born of greed, and battle against it for survival.
Stars: Park Seo-joon, Han So-hee, Wi Ha-joon, Kim Hae-sook
Votes: 10,350
29. They Cloned Tyrone (2023)
R | 122 min | Comedy, Mystery, Sci-Fi
A series of eerie events thrusts an unlikely trio onto the trail of a nefarious government conspiracy in this pulpy mystery caper.
Director: Juel Taylor | Stars: John Boyega, Jamie Foxx, Teyonah Parris, Kiefer Sutherland
Votes: 40,813
30. The Promised Neverland (2019–2021)
TV-14 | 23 min | Animation, Action, Adventure
When three gifted kids at an isolated idyllic orphanage discover the secret and sinister purpose they were raised for, they look for a way to escape from their evil caretaker and lead the other children in a risky escape plan.
Stars: Sumire Morohoshi, Mariya Ise, Shinei Ueki, Lynn
Votes: 47,166
31. Three Identical Strangers (2018)
PG-13 | 96 min | Documentary, Biography, Drama
In 1980 New York, three young men who were all adopted meet each other and find out they're triplets who were separated at birth. But their quest to find out why turns into a bizarre and sinister mystery.
Director: Tim Wardle | Stars: Robert Shafran, Michael Domnitz, Howard Schneider, Ellen Cervone
Votes: 40,109 | Gross: $12.32M
32. Species II (1998)
R | 93 min | Action, Horror, Sci-Fi
An astronaut gets infected with alien DNA during the first mission on Mars and runs amok on earth. Preston and Laura team up with a peaceful, genetically re-engineered Sil to track the monster down.
Director: Peter Medak | Stars: Natasha Henstridge, Michael Madsen, Marg Helgenberger, Mykelti Williamson
Votes: 31,378 | Gross: $19.17M
33. Frankenstein (1931)
Passed | 70 min | Drama, Horror, Sci-Fi
Dr Henry Frankenstein is obsessed with assembling a living being from parts of several exhumed corpses.
Director: James Whale | Stars: Colin Clive, Mae Clarke, Boris Karloff, John Boles
Votes: 79,911
34. Project Power (2020)
R | 113 min | Action, Crime, Sci-Fi
When a pill that gives its users unpredictable superpowers for five minutes hits the streets of New Orleans, a teenage dealer and a local cop must team with an ex-soldier to take down the group responsible for its creation.
Directors: Henry Joost, Ariel Schulman | Stars: Jamie Foxx, Joseph Gordon-Levitt, Dominique Fishback, Rodrigo Santoro
Votes: 97,968
35. Resident Evil: Afterlife (2010)
R | 96 min | Action, Horror, Sci-Fi
While still out to destroy the evil Umbrella Corporation, Alice joins a group of survivors living in a prison surrounded by the infected who also want to relocate to the mysterious but supposedly unharmed safe haven known only as Arcadia.
Director: Paul W.S. Anderson | Stars: Milla Jovovich, Ali Larter, Wentworth Miller, Kim Coates
Votes: 179,453 | Gross: $60.13M
36. Disturbing Behavior (1998)
R | 84 min | Horror, Mystery, Sci-Fi
The new kid in Cradle Bay, Washington stumbles across something sinister about the town's method of transforming its unruly teens into upstanding citizens.
Director: David Nutter | Stars: James Marsden, Katie Holmes, Nick Stahl, Tobias Mehler
Votes: 25,351 | Gross: $17.41M
37. Pi (1998)
R | 84 min | Drama, Horror, Mystery
A paranoid mathematician searches for a key number that will unlock the universal patterns found in nature.
Director: Darren Aronofsky | Stars: Sean Gullette, Mark Margolis, Ben Shenkman, Pamela Hart
Votes: 186,643 | Gross: $3.22M
38. Helix (2014–2015)
TV-PG | 40 min | Drama, Horror, Mystery
A team of scientists are thrust into a potentially life-or-death situation when they arrive in the Arctic to secretly investigate what could be an outbreak of a strange disease in a secluded international research facility.
Stars: Billy Campbell, Kyra Zagorsky, Mark Ghanimé, Jordan Hayes
Votes: 30,625
39. The Experiment (2010)
R | 96 min | Drama, Thriller
26 men are chosen to participate in the roles of guards and prisoners in a psychological study that ultimately spirals out of control.
Director: Paul T. Scheuring | Stars: Adrien Brody, Cam Gigandet, Forest Whitaker, Maggie Grace
Votes: 57,249
40. The Titan (2018)
TV-MA | 97 min | Drama, Mystery, Romance
A military family takes part in a ground-breaking experiment of genetic evolution and space exploration.
Director: Lennart Ruff | Stars: Sam Worthington, Taylor Schilling, Tom Wilkinson, Agyness Deyn
Votes: 33,508
41. The Unborn (2009)
PG-13 | 88 min | Horror, Mystery, Thriller
A young woman fights the spirit that is slowly taking possession of her.
Director: David S. Goyer | Stars: Odette Annable, Gary Oldman, Cam Gigandet, Meagan Good
Votes: 53,382 | Gross: $42.67M
42. Generation X (1996 TV Movie)
TV-PG | 87 min | Action, Adventure, Sci-Fi
The new teenage students at a school for mutants (normal-looking humans with fantastic powers) try to stop an evil scientist from controlling the world's dreams.
Director: Jack Sholder | Stars: Matt Frewer, Finola Hughes, Jeremy Ratchford, Heather McComb
Votes: 2,037
43. Sky Captain and the World of Tomorrow (2004)
PG | 106 min | Action, Adventure, Mystery
After New York City receives a series of attacks from giant flying robots, a reporter teams up with a pilot in search of their origin, as well as the reason for the disappearances of famous scientists around the world.
Director: Kerry Conran | Stars: Gwyneth Paltrow, Jude Law, Angelina Jolie, Giovanni Ribisi
Votes: 87,543 | Gross: $37.76M
44. Taken (2002)
TV-PG | 68 min | Drama, Mystery, Sci-Fi
Three families experience alien abductions over a period of five decades.
Stars: Dakota Fanning, Matt Frewer, Emily Bergl, Heather Donahue
Votes: 21,036
45. Martyrs (2015)
Not Rated | 86 min | Drama, Horror, Thriller
A woman and her childhood friend seek out revenge on those who victimized and abused them.
Directors: Kevin Goetz, Michael Goetz | Stars: Troian Bellisario, Bailey Noble, Kate Burton, Caitlin Carmichael
Votes: 6,939
46. Captain America (1990)
PG-13 | 97 min | Action, Adventure, Sci-Fi
Frozen in the ice for decades, Captain America is freed to battle against archcriminal The Red Skull.
Director: Albert Pyun | Stars: Matt Salinger, Ronny Cox, Ned Beatty, Darren McGavin
Votes: 15,157 | Gross: $0.01M
47. Return of the Living Dead III (1993)
R | 97 min | Horror
Having recently witnessed the horrific results of a top secret project to bring the dead back to life, a distraught youth performs the operation on his girlfriend after she's killed in a motorcycle accident.
Director: Brian Yuzna | Stars: J. Trevor Edmond, Melinda Clarke, Kent McCord, James T. Callahan
Votes: 16,786 | Gross: $0.05M
48. The Lazarus Effect (2015)
PG-13 | 83 min | Horror, Mystery, Sci-Fi
A group of medical researchers discover a way to bring dead patients back to life.
Director: David Gelb | Stars: Olivia Wilde, Mark Duplass, Evan Peters, Sarah Bolger
Votes: 46,218 | Gross: $25.80M
49. The X Files: I Want to Believe (2008)
PG-13 | 104 min | Crime, Drama, Horror
Mulder and Scully are called back to duty by the FBI when a former priest claims to be receiving psychic visions pertaining to a kidnapped agent.
Director: Chris Carter | Stars: David Duchovny, Gillian Anderson, Billy Connolly, Amanda Peet
Votes: 94,069 | Gross: $20.98M
50. The Experiment (2001)
R | 120 min | Drama, Thriller
For two weeks, 20 male participants are hired to play prisoners and guards in a prison. The "prisoners" have to follow seemingly mild rules, and the "guards" are told to retain order without using physical violence.
Director: Oliver Hirschbiegel | Stars: Moritz Bleibtreu, Christian Berkel, Oliver Stokowski, Wotan Wilke Möhring
Votes: 96,185 | Gross: $0.14M