Sort by Popularity - Most Popular Movies and TV Shows tagged with keyword "experiment"
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51. Splice (2009)
R | 104 min | Horror, Sci-Fi
Genetic engineers Clive Nicoli and Elsa Kast hope to achieve fame by successfully splicing together the DNA of different animals to create new hybrid animals for medical use.
Director: Vincenzo Natali | Stars: Adrien Brody, Sarah Polley, Delphine Chanéac, Brandon McGibbon
Votes: 102,022 | Gross: $17.00M
52. Allegiant (2016)
PG-13 | 120 min | Action, Adventure, Mystery
After the earth-shattering revelations of Insurgent, Tris must escape with Four beyond the wall that encircles Chicago, to finally discover the shocking truth of the world around them.
Director: Robert Schwentke | Stars: Shailene Woodley, Theo James, Jeff Daniels, Naomi Watts
Votes: 134,870 | Gross: $66.18M
53. The Nightmare Before Christmas (1993)
PG | 76 min | Animation, Family, Fantasy
Jack Skellington, king of Halloween Town, discovers Christmas Town, but his attempts to bring Christmas to his home causes confusion.
Director: Henry Selick | Stars: Danny Elfman, Chris Sarandon, Catherine O'Hara, William Hickey
Votes: 376,233 | Gross: $75.08M
54. Lorenzo's Oil (1992)
PG-13 | 129 min | Biography, Drama
Lorenzo Odone, a Virginia 5-year-old, develops a degenerative nerve disease so rare that nobody is working on a cure, so his parents decide to immerse themselves in research and tackle the problem themselves.
Director: George Miller | Stars: Nick Nolte, Susan Sarandon, Peter Ustinov, Kathleen Wilhoite
Votes: 24,183 | Gross: $7.29M
55. Hollow Man (2000)
R | 112 min | Action, Horror, Sci-Fi
A brilliant scientist's discovery renders him invisible, but transforms him into an omnipotent, dangerous megalomaniac.
Director: Paul Verhoeven | Stars: Kevin Bacon, Elisabeth Shue, Josh Brolin, Kim Dickens
Votes: 138,762 | Gross: $73.21M
56. The Time Machine (2002)
PG-13 | 96 min | Action, Adventure, Sci-Fi
Hoping to alter the events of the past, a 19th century inventor instead travels 800,000 years into the future, where he finds humankind divided into two warring races.
Director: Simon Wells | Stars: Guy Pearce, Yancey Arias, Mark Addy, Phyllida Law
Votes: 130,694 | Gross: $56.68M
57. Spiderhead (2022)
R | 106 min | Action, Crime, Drama
In the near future, convicts are offered the chance to volunteer as medical subjects to shorten their sentence. One such subject for a new drug capable of generating feelings of love begins questioning the reality of his emotions.
Director: Joseph Kosinski | Stars: Chris Hemsworth, Miles Teller, Jurnee Smollett, Mark Paguio
Votes: 66,768
58. Superhero Movie (2008)
PG-13 | 75 min | Action, Comedy, Sci-Fi
Orphaned high school student Rick Riker is bitten by a radioactive dragonfly, develops super powers (except for the ability to fly), and becomes a hero.
Director: Craig Mazin | Stars: Drake Bell, Leslie Nielsen, Sara Paxton, Christopher McDonald
Votes: 75,995 | Gross: $26.64M
59. High Life (2018)
R | 113 min | Mystery, Sci-Fi, Thriller
A father and his daughter struggle to survive in deep space where they live in isolation.
Director: Claire Denis | Stars: Robert Pattinson, Juliette Binoche, André 3000, Mia Goth
Votes: 41,282 | Gross: $1.23M
60. Oculus (2013)
R | 104 min | Horror, Mystery, Thriller
A recently released inmate from a mental asylum learns from his sister that the murders he was convicted of committing were actually orchestrated by a supernatural entity, the Lasser Glass mirror.
Director: Mike Flanagan | Stars: Karen Gillan, Brenton Thwaites, Katee Sackhoff, Rory Cochrane
Votes: 140,181 | Gross: $27.70M
61. Deep Blue Sea (1999)
R | 105 min | Action, Adventure, Sci-Fi
Searching for a cure to Alzheimer's disease, a group of scientists on an isolated research facility become the prey, as a trio of intelligent sharks fight back.
Director: Renny Harlin | Stars: Thomas Jane, Saffron Burrows, Samuel L. Jackson, Jacqueline McKenzie
Votes: 142,921 | Gross: $73.65M
62. Firestarter (2022)
R | 94 min | Drama, Horror, Sci-Fi
A young girl tries to understand how she mysteriously gained the power to set things on fire with her mind.
Director: Keith Thomas | Stars: Zac Efron, Ryan Kiera Armstrong, Sydney Lemmon, Michael Greyeyes
Votes: 22,436
63. The Wilds (2020–2022)
TV-14 | 60 min | Adventure, Drama, Mystery
A group of teens must survive after a plane crash leaves them stranded on a deserted island. The girls tell their stories to investigators who slowly piece together what happened to them.
Stars: Rachel Griffiths, Sophia Ali, Shannon Berry, Jenna Clause
Votes: 25,295
64. The Island of Dr. Moreau (1996)
PG-13 | 96 min | Horror, Sci-Fi, Thriller
After being rescued and brought to an island, a man discovers that its inhabitants are experimental animals being turned into strange-looking humans, all of it the work of a visionary doctor.
Directors: John Frankenheimer, Richard Stanley | Stars: David Thewlis, Marlon Brando, Val Kilmer, Fairuza Balk
Votes: 35,578 | Gross: $27.66M
65. Push (2009)
PG-13 | 111 min | Action, Sci-Fi, Thriller
Two young Americans with special abilities must race to find a girl in Hong Kong before a shadowy government organization called Division does.
Director: Paul McGuigan | Stars: Camilla Belle, Dakota Fanning, Chris Evans, Colin Ford
Votes: 115,775 | Gross: $31.81M
66. Monsters vs. Aliens (2009)
PG | 94 min | Animation, Action, Adventure
A woman transformed into a giant after she is struck by a meteorite on her wedding day becomes part of a team of monsters sent in by the U.S. government to defeat an alien mastermind trying to take over Earth.
Directors: Rob Letterman, Conrad Vernon | Stars: Reese Witherspoon, Rainn Wilson, Stephen Colbert, Seth Rogen
Votes: 176,718 | Gross: $198.35M
67. Real Genius (1985)
PG | 108 min | Comedy, Romance, Sci-Fi
An uptight teenage prodigy enters a top engineering college, but feels awkward among the freewheeling students. When a professor aims to turn their laser project into a military weapon, he and his offbeat roommate plot to ruin the plan.
Director: Martha Coolidge | Stars: Val Kilmer, Stacy Peralta, Daniel Ades, Andres Aybar
Votes: 37,899 | Gross: $13.00M
68. Flatliners (2017)
PG-13 | 109 min | Drama, Horror, Mystery
Five medical students, obsessed by what lies beyond the confines of life, embark on a daring experiment: by stopping their hearts for short periods, each triggers a near-death experience - giving them a firsthand account of the afterlife.
Director: Niels Arden Oplev | Stars: Elliot Page, Diego Luna, Nina Dobrev, James Norton
Votes: 51,122 | Gross: $16.88M
69. The Dam Busters (1955)
Approved | 105 min | Drama, History, War
Drama based on the attempt by the RAF to destroy six dams in Germany during World War II.
Director: Michael Anderson | Stars: Richard Todd, Michael Redgrave, Ursula Jeans, Basil Sydney
Votes: 11,424
70. The Powerpuff Girls (1998–2004)
TV-Y7-FV | 30 min | Animation, Action, Adventure
Three super-powered little girls constantly save the world (or at least the city of Townsville) from monsters, would-be conquerers and a few other gross things.
Stars: Cathy Cavadini, Elizabeth Daily, Tara Strong, Tom Kenny
Votes: 48,150
71. Mirage (2018)
TV-MA | 128 min | Drama, Fantasy, Mystery
Two storms separated by 25 years. A woman murdered. A daughter missed. Only 72 hours to discover the truth.
Director: Oriol Paulo | Stars: Adriana Ugarte, Chino Darín, Javier Gutiérrez, Álvaro Morte
Votes: 64,662
72. The Golden Compass (2007)
PG-13 | 113 min | Adventure, Family, Fantasy
In a parallel universe, young Lyra Belacqua journeys to the far North to save her best friend and other kidnapped children from terrible experiments by a mysterious organization.
Director: Chris Weitz | Stars: Nicole Kidman, Daniel Craig, Dakota Blue Richards, Ben Walker
Votes: 197,151 | Gross: $70.11M
73. The Haunting (1999)
PG-13 | 113 min | Fantasy, Horror, Mystery
Dr Marrow enlists Theo, Luke and Nell for a study of sleep disorders at the Hill House. As soon as the terrifying truth about the mansion is revealed, everyone is found fighting for their lives.
Director: Jan de Bont | Stars: Liam Neeson, Catherine Zeta-Jones, Owen Wilson, Lili Taylor
Votes: 80,699 | Gross: $91.41M
74. Red Lights (2012)
R | 114 min | Drama, Fantasy, Mystery
Psychologist Margaret Matheson and her assistant debunk paranormal activity, which leads them to investigate a world-renowned psychic who has resurfaced after many years out of the limelight following the suspicious death of his toughest critic.
Director: Rodrigo Cortés | Stars: Sigourney Weaver, Robert De Niro, Cillian Murphy, Elizabeth Olsen
Votes: 66,338 | Gross: $0.05M
75. Daybreakers (2009)
R | 98 min | Action, Horror, Sci-Fi
In the year 2019, a plague has transformed almost every human into vampires. Faced with a dwindling blood supply, the fractured dominant race plots their survival; meanwhile, a researcher works with a covert band of vamps on a way to save humankind.
Directors: Michael Spierig, Peter Spierig | Stars: Ethan Hawke, Willem Dafoe, Sam Neill, Harriet Minto-Day
Votes: 135,274 | Gross: $30.10M
76. Around the World in 80 Days (2004)
PG | 120 min | Action, Adventure, Comedy
To win a bet, an eccentric British inventor embarks, with his Chinese valet and an aspiring French artist, on a trip full of adventures and dangers around the world in exactly 80 days.
Director: Frank Coraci | Stars: Jackie Chan, Steve Coogan, Jim Broadbent, Kathy Bates
Votes: 94,976 | Gross: $24.01M
77. MythBusters (2003–2018)
TV-PG | 44 min | Documentary, Mystery, Reality-TV
A weekly documentary in which two Hollywood special effects experts attempt to debunk urban legends by directly testing them.
Stars: Robert Lee, Jamie Hyneman, Adam Savage, Kari Byron
Votes: 54,902
78. The Box (I) (2009)
PG-13 | 115 min | Drama, Mystery, Thriller
With the press of a button, a wooden box bestows riches and death.
Director: Richard Kelly | Stars: Cameron Diaz, James Marsden, Frank Langella, James Rebhorn
Votes: 95,521 | Gross: $15.05M
79. Mary Shelley's Frankenstein (1994)
R | 123 min | Drama, Horror, Romance
When the brilliant but unorthodox scientist Dr. Victor Frankenstein rejects the artificial man that he has created, the Creature escapes and later swears revenge.
Director: Kenneth Branagh | Stars: Robert De Niro, Kenneth Branagh, Helena Bonham Carter, Tom Hulce
Votes: 59,483 | Gross: $22.01M
80. Universal Soldier (1992)
R | 102 min | Action, Sci-Fi
Soldiers who were killed in action are brought back to life in a top secret military experiment that creates superhuman warriors.
Director: Roland Emmerich | Stars: Jean-Claude Van Damme, Dolph Lundgren, Ally Walker, Ed O'Ross
Votes: 96,547 | Gross: $36.30M
81. Resident Evil: Retribution (2012)
R | 95 min | Action, Horror, Sci-Fi
Alice fights alongside a resistance movement to regain her freedom from an Umbrella Corporation testing facility.
Director: Paul W.S. Anderson | Stars: Milla Jovovich, Sienna Guillory, Michelle Rodriguez, Aryana Engineer
Votes: 150,566 | Gross: $42.35M
82. Elfen Lied (2004)
TV-MA | 24 min | Animation, Action, Drama
Two university students come across a seemingly harmless girl named Lucy, unaware that she's actually a mutant serial killer with a split personality.
Stars: Sanae Kobayashi, Chihiro Suzuki, Mamiko Noto, Sam Saletta
Votes: 37,139
83. Firestarter (1984)
R | 114 min | Action, Horror, Sci-Fi
A couple who participated in a potent medical experiment gain telepathic ability and then have a child who is pyrokinetic.
Director: Mark L. Lester | Stars: Drew Barrymore, David Keith, Freddie Jones, Heather Locklear
Votes: 37,081 | Gross: $15.10M
84. Outbreak (1995)
R | 127 min | Action, Drama, Thriller
Army doctors struggle to find a cure for a deadly virus spreading throughout a California town that was brought to America by an African monkey.
Director: Wolfgang Petersen | Stars: Dustin Hoffman, Rene Russo, Morgan Freeman, Kevin Spacey
Votes: 138,223 | Gross: $67.82M
85. Re-Animator (1985)
Unrated | 84 min | Comedy, Horror, Sci-Fi
After an odd new medical student arrives on campus, a dedicated local and his girlfriend become involved in bizarre experiments centering around the re-animation of dead tissue.
Director: Stuart Gordon | Stars: Jeffrey Combs, Bruce Abbott, Barbara Crampton, David Gale
Votes: 71,801 | Gross: $2.02M
86. The Girl with All the Gifts (2016)
R | 111 min | Action, Adventure, Drama
A scientist and a teacher living in a dystopian future embark on a journey of survival with a special young girl named Melanie.
Director: Colm McCarthy | Stars: Sennia Nanua, Fisayo Akinade, Dominique Tipper, Paddy Considine
Votes: 64,654
87. Zoo (2015–2017)
TV-14 | 42 min | Drama, Mystery, Sci-Fi
A team comes together and searches to find out what's causing a rash of violent animal attacks.
Stars: James Wolk, Kristen Connolly, Nonso Anozie, Billy Burke
Votes: 26,136
88. The Secret of NIMH (1982)
G | 82 min | Animation, Adventure, Drama
To save her ill son, a field mouse must seek the aid of a colony of rats, with whom she has a deeper link than she suspected.
Director: Don Bluth | Stars: Elizabeth Hartman, Derek Jacobi, Dom DeLuise, Arthur Malet
Votes: 45,395 | Gross: $10.14M
89. Quarantine (2008)
R | 89 min | Horror, Sci-Fi, Thriller
A television reporter and her cameraman are trapped inside a building quarantined by the CDC, after the outbreak of a mysterious virus which turns humans into bloodthirsty killers.
Director: John Erick Dowdle | Stars: Jennifer Carpenter, Steve Harris, Columbus Short, Jay Hernandez
Votes: 77,685 | Gross: $31.69M
90. Day of the Dead (1985)
Not Rated | 101 min | Horror, Thriller
As the world is overrun by zombies, a group of scientists and military personnel sheltering in an underground bunker in Florida must decide on how they should deal with the undead horde.
Director: George A. Romero | Stars: Lori Cardille, Terry Alexander, Joseph Pilato, Jarlath Conroy
Votes: 74,637 | Gross: $5.80M
91. From Beyond (1986)
R | 85 min | Horror, Sci-Fi
A group of scientists have developed the Resonator, a machine which allows whoever is within range to see beyond normal perceptible reality. But when the experiment succeeds, they are immediately attacked by terrible life forms.
Director: Stuart Gordon | Stars: Jeffrey Combs, Barbara Crampton, Ted Sorel, Ken Foree
Votes: 30,962 | Gross: $1.26M
92. Swamp Thing (1982)
PG | 91 min | Horror, Sci-Fi
After a violent incident with a special chemical, a research scientist is turned into a swamp plant monster.
Director: Wes Craven | Stars: Louis Jourdan, Adrienne Barbeau, Ray Wise, David Hess
Votes: 16,522
93. Bio-Dome (1996)
PG-13 | 88 min | Comedy
Moronic best friends get themselves locked inside the Bio-Dome, a science experiment, along with a group of environmental scientists for one year.
Director: Jason Bloom | Stars: Pauly Shore, Stephen Baldwin, William Atherton, Denise Dowse
Votes: 29,854 | Gross: $26.76M
94. The Innocents (2021)
Not Rated | 117 min | Drama, Fantasy, Horror
During the bright Nordic summer, a group of children reveal their dark and mysterious powers when the adults aren't looking. In this original and gripping supernatural thriller, playtime takes a dangerous turn.
Director: Eskil Vogt | Stars: Rakel Lenora Petersen Fløttum, Alva Brynsmo Ramstad, Sam Ashraf, Mina Yasmin Bremseth Asheim
Votes: 25,108
95. Piranha (1978)
R | 94 min | Comedy, Horror, Sci-Fi
When flesh-eating piranhas are accidentally released into a summer resort's rivers, the guests become their next meal.
Director: Joe Dante | Stars: Bradford Dillman, Heather Menzies-Urich, Kevin McCarthy, Keenan Wynn
Votes: 24,905 | Gross: $6.00M
96. Altered States (1980)
R | 102 min | Horror, Sci-Fi, Thriller
A psycho-physiologist experiments with drugs and a sensory-deprivation tank and has visions he believes are genetic memories.
Director: Ken Russell | Stars: William Hurt, Blair Brown, Bob Balaban, Charles Haid
Votes: 38,788 | Gross: $19.85M
97. The Brood (1979)
R | 92 min | Horror, Sci-Fi
A man tries to uncover an unconventional psychologist's therapy techniques on his institutionalized wife, amidst a series of brutal murders.
Director: David Cronenberg | Stars: Oliver Reed, Samantha Eggar, Art Hindle, Henry Beckman
Votes: 34,475
98. 40 Days and 40 Nights (2002)
R | 96 min | Comedy, Romance
After a brutal break-up, a young man vows to stay celibate during the forty days of Lent, but finds the girl of his dreams and is unable to do anything about it.
Director: Michael Lehmann | Stars: Josh Hartnett, Shannyn Sossamon, Paulo Costanzo, Adam Trese
Votes: 75,928 | Gross: $37.95M
99. Beakman's World (1992–1997)
TV-PG | 30 min | Comedy, Family
A wacky scientist and his companions answer viewer questions about science.
Stars: Paul Zaloom, Mark Ritts, Eliza Schneider, Alanna Ubach
Votes: 2,996
100. Phenomena (1985)
R | 116 min | Crime, Horror, Mystery
A young girl who has an amazing ability to communicate with insects is transferred to an exclusive Swiss boarding school, where her unusual capability might help solve a string of murders.
Director: Dario Argento | Stars: Jennifer Connelly, Donald Pleasence, Daria Nicolodi, Dalila Di Lazzaro
Votes: 30,201