An illegal drug shipment arriving in New York City must be found before the narcotics flood the streets; Jamie helps a neighbor handle a gambling debt; Frank receives push back from Mayor Chase over his handling of a brawl.
Danny pursues a con artist pretending to be the legendary singer Jimmy Buffett; Frank investigates an impressive police captain who is using her badge to get free wares from local stores.
Frank is at odds with his friend Archbishop Kearns when he says the NYPD arrested the wrong man for a murder; Eddie tries to get justice for a sexual assault survivor; Jamie and his nephew, Joe Hill, butt heads over fair police practices.
Frank contends with a potentially dirty cop within his ranks; Eddie and Badillo track down the culprits behind the theft of valuable, rare works from a celebrated bookstore; Erin snoops into the background of a new woman in Anthony's life.
Erin's nephew, police officer Joe Hill, becomes aware of witness tampering in a trial; Baez forces Danny to help her find the killer of her favorite TV personality; Eddie questions her decision to become a police sergeant.
Frank contends with public outcry to defund the NYPD School Safety Division, after a physical altercation between a school officer and a student goes viral; Danny and Baez help a father track down his missing ex-wife and daughter.
Frank, Baker, Garrett and Gormley experience guilt when an officer they briefly worked with is shot after Frank reassigned her for not meshing with their team; Anthony is offered a promotion that strains his relationship with Erin.
Frank is blindsided when Mayor Chase bypasses him with a request for Jamie to head his security detail; Danny and Baez investigate the attempted murder of a wealthy college student; Anthony fears money woes are leading his sibling down the wrong path.
An encounter with an old rival leads Erin to look into an alleged wrongful conviction; Jamie is torn over whether to report a sergeant; Danny and Baez look for an abducted child.
Erin is stalked by a man who was recently released from prison; Jamie works to save his badge when he is caught driving under the influence after he is unknowingly given drugs at a party; Frank navigates multiple family issues.
Jamie and Joe search for an undocumented teenage girl who has been sex-trafficked; a woman in witness protection is murdered; Frank calls out the district attorney's office for instituting a new rule.
Frank announces he will not endorse Erin's run for district attorney; Danny and Baez investigate a bloody crime scene at a hotel; Jamie begins a new job as a field intelligence sergeant that requires him to keep secrets from his family.
Danny and Baez investigate after a vicious attack leaves their mutual friend hospitalized; Frank and the team debate the appropriate memorial protocol for a former police commissioner with a questionable professional legacy.
Danny and Baez investigate a series of violent robberies targeting luxury timepieces; Erin is conflicted about criminally charging a potentially innocent man; Frank is forced to reopen a case in which the officer involved was acquitted.
Frank launches an investigation after the Reagan family is harassed; Danny and Baez form an unlikely partnership with an informant in order to prevent a murder; Eddie lands in hot water after she defies a direct order.
Danny and Jamie clash over a gang-related shooting; Erin and Anthony search for answers when a lawyer in their office jeopardizes a case involving Erin's nephew; Frank grows concerned when he's not invited to speak at a policing forum.
Erin and Anthony clash when Anthony's daughter is the sole eyewitness to a fatal shooting; Frank wants to punish an off-duty cop for his inaction during an armed robbery; Danny and Baez investigate a violent mugging.
Danny crosses paths with a criminal from a previous case when he investigates a gang attack with a shocking motive; Frank and Mayor Chase butt heads over an off-duty cop who goes too far making a political statement.