I you ask which is the best Mexican (or even latin-american) comic show it is without any doubt Chespirito. All of Roberto Gómez Bolaños characters became icons of the popular culture, including: El Chavo del 8, El Chapulín Colorado, El Chómpiras, Chaparrón Bonaparte, etc (notice the trademark letter "CH" in every name). If you happen to have a chance to watch the re-runs on Mexican TV (Televisa) do it, you'll have a loud laugh with other characters such as Quico, Don Ramón, El Profesor Jirafales and many more. Too bad that the show became a little slow on it's last days, but anyway the best are the early episodes.