Anna seems totally ignorant about the basic facts regarding bone marrow donation, she asks Dr. Romano what the procedure involves, and asks Carter what he means when he said she will be sore for a few days; one doesn't need to be a surgeon to understand that several large needles being inserted into your pelvis is going to cause a little pain for a few days. As a medical doctor Anna would have learned the basics of this procedure in the parts of medical school that covered the subjects of oncology and surgery.