- In the mid-1950s, Hathout was imprisoned in Cairo, Egypt, for protesting against the military dictatorship.
- Maher Hathout founded the Muslim Public Affairs Council with offices in both Los Angeles, California, and Washington, D.C.
- Joining with some Christian and Jewish representatives, Hathout spoke out on various social issues including U.S wars in the Middle East, the spread of nuclear weapons and against the philosophy advocated by radical Islamic extremists.
- Hathout urged President William Clinton and President George W. Bush to improve political relationships within the Muslim world.
- Maher Hathout was Chairman and later Chief Spokesperson for the Islamic Center of Los Angeles for about three decades.
- In Los Angeles, California, Maher Hathout founded the New Horizon School, the city's first Islamic private school.
- In 2006, the Los Angeles County Human Relations Commission awarded him the 'John Allen Buggs Award' for his humanitarian efforts. However, various Jewish representatives opposed this honor because Hathout once called Irael an "apartheid state.".
- Father of Gasser Hathout and Samer Hathout-Blackshire. He has 4 grandchildren.
- After medical school studies in Egypt, Hathou immigrated to Buffalo, New York, and then to Los Angeles, California, where he was a cardiologist.
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