- Took him a total of 14 months to lose 24½ pounds he gained from eating McDonalds.
- Was rejected by the film school at USC five times.
- Had done standup comedy briefly in Los Angeles and was, at one point homeless before finding firmer ground as a filmmaker.
- He gained 25 pounds eating nothing but McDonald's for a month for Super Size Me (2004).
- His favorite films included Scanners (1981), It Happened One Night (1934) and The Shawshank Redemption (1994). His favorite documentary was Brother's Keeper (1992) and his favorite dramatic film was A Face in the Crowd (1957).
- Son, Laken James Spurlock, born at home on 9 December 2006.
- [2005] Engaged to longtime girlfriend Alexandra Jamieson.
- Graduated from NYU with a film degree in 1993.
- Was a member of Phi Gamma Delta national fraternity (Nu Epsilon chapter - New York University).
- He and Alex got married on Tavarua Island in Fiji.
- Currently lives in New York City, New York. (2005)
- Member of the ACLU.
- Developed fatty liver disease, which he blamed on a diet of fast food. However, he later admitted in 2017 that he had a longtime alcohol abuse issue since the age of 13, which was never disclosed in his documentaries such as Super Size Me (2004).
- Was the founder of the New York-based production studio Warrior Poets.
- Graduated from Woodrow Wilson High School in Beckley, West Virginia.
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