- He appeared in two Best Picture Academy Award winners: Wings (1927) and It Happened One Night (1934).
- Father of Todd Karns.
- He has appeared in six films that have been selected for the National Film Registry by the Library of Congress as being "culturally, historically or aesthetically" significant: Wings (1927), The Jazz Singer (1927), It Happened One Night (1934), Twentieth Century (1934), His Girl Friday (1940) and Woman of the Year (1942).
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