This is the debut of Kara's new skirtless superhero suit. The costume's cape was the major reason for the redesign, as it was so heavy that Melissa Benoist needed to wear a corset to be able to fight in it.
In the DC comics, M1dn1ght was computer code incarnate created by Lena Luthor and unintentionally brought to life by Superwoman, M1dn1ght was programmed to free Lena from her dimensional prison.
Brainiac mentions Takron-Galtos in a conversation with Supergirl. In the Legion of Super-Heroes continuity, by the 30th Century T-G serves as the "prison planet" for the United Planets. In comics dating to 2011, it was revealed that Takron-Galtos is actually the planet Earth after humanity has abandoned their home planet and moved to the artificially-constructed New Earth.
Andrea Rojas also appeared in the Smallville (2001) episode "Vengeance (2006)". Rather than her comics counterpart Acrata, she adopts the moniker Angel of Vengeance and operates as a Batman-ish vigilante.
Andrea's plans for a "new CatCo" involve transforming it from an award-winning and trusted news magazine to a revenue-driven content farm focusing on "clicks" more than serious writing. Just days before the episode premiered, Sports Illustrated cut over 40 percent of its staffers and announced a plan much like Andrea's own.