Filmed over the course of 12 months, this first edition of the series meets Lucas as he begins the transition from female to male and undergoes surgery to have his breasts removed.
This edition follows 52-year-old virgin Emma as she prepares for breast augmentation, writer Juno who grew up thinking she was a gay man and ex-firefighter Stephanie who up until 18 months ago was called Mark.
The series concludes by looking at some of the range of procedures the clinic performs. A patient at the beginning of her transition from male to female prepares to explain to her young son that his father is now a woman.