During the opening titles, when Maggie pops out of the grocery bag, she is holding a jug of Szechuan sauce. This is probably a reference to another animated show, 'Rick and Morty,' in which they referenced the Szechuan dipping sauce that used to be served at McDonald's.
Miss Hoover's blackboard says: "Five states whose capitals start with the same letter as the state: Delaware, Hawaii, Indiana, Oklahoma, this state" therefore once again keeping Springfield's location a secret.
Bart's chalkboard gag: Hooligan is not a profession.
According to Homer's "Moon Weight" of 182 lbs he would weigh roughly 1,103.5 lbs on Earth. (1,103.5 x 0.165 = 182.0775)