The scene in which Dominic is crossing the desert was shot in Glamis Dunes, California.
The car Dominic drives , 1966 Oldsmobile Delta '88, appeared in the film ALMOST FAMOUS, also shot in San Diego.
The car Dominic drives most of the movie is named Sweet Lil Darlin; it's a 1966 Oldsmobile Delta '88.
The diner scene is comprised of two locations. The exterior is JAY'S SOUTHERN CAFE, in Jacumba, CA. The interior is the ANTIQUE ROW CAFE, in San Diego.
66 & NOWHERE is a remake of 1945's film noir classic DETOUR.