"Becca on Call" was originally a 3 page scene that Jenness Rouse wrote (and performed in) for her demo reel.
The story is loosely inspired by and a parody of Jenness's life, an aspiring actress working as an office assistant in her family's nonprofit organization.
While scouting locations for filming, Jenness and her crew considered using the very nonprofit organization's facility where Jenness had worked as an office assistant. However, they opted to use a local eye clinic instead.
The name of the show, "Becca on Call," is a play-on words for "Beck and Call" and being "On Call" (Becca is an assistant at the "Beck and Call" of all the "On Call" nurses and House Call patients)