This is the first episode where Sophie Krustofski speaks since her first appearance (Insane Clown Poppy (2000)). Natasha Lyonne has replaced Drew Barrymore.
Gnome in a home is a parody of an Elf on the Shelf which like the elf is in a different location each day.
When Marge puts the Gnome in your Home on Maggie's shelf, briefly visible is a book entitled "The Fat in the Hat," a callback to a Dr. Seuss parody used on a recent Halloween special.
The line that Krusty uses, 'Can we get some room tone, just 20 seconds' is the same line that Chris Griffin uses in Carter and Tricia (2016).
Apu comments that the Hindu god Ganesh could be a Pixar hero. In fact, there was a Pixar short in which several Hindu gods are depicted as superheroes.