We learn Agent Mike's real name is Darryl.
Richard Bekins, who plays Jean-Pierre Morneau, also plays Hank Atwood, the businessman who dies for lack of NZT, in Limitless (2011).
Howard Stern's longtime limo driver, Ronnie Mund, guest stars as Special Agent Mundt of the FBI.
At the time of airing, CBS had not committed to a second season. They ultimately chose not to pick up the option.
The box of donuts Brian presents to the Canadian and Greenland delegates in his hallucination is from Tim Horton's, a quintessential Canadian donut franchise.