The makers came up with the idea during a drunk night while in college. The room in the first scene is modeled after the room they were in at that moment.
There are many references to music in the film. A previous clip the directors made for Dutch singer Gers Pardoel is mentioned on a poster. And there is sign from band Happy Campers, who made the song featured in the film.
A Single Life was screened in the Netherlands as a preview before blockbuster Gooische Vrouwen 2. The comedy was the best visited Dutch feature in about 20 years.