Oliver is three days older than Kaz in Mighty Med (2013) but in real life Jake Short is 1 1/2 years older than Bradley Steven Perry.
Troy Brenna, who plays Brain Matter's green monster form, is also the motion capture actor for the Hulk in Avengers: Age of Ultron (2015) and the stunt double for the Hulk in Hulk (2003) and The Avengers (2012)
When Oliver (jake short) has a dream and helps write a comic book, he has to change his name so his mother won't realize he's writing comics instead of studying. So Kaz (Bradley Steven perry) suggests the name Quimby Fletcher, which is the reverse of the name of Jake Short's character from another Disney channel show, ANT Farm. There, Jake Short plays Fletcher Quimby.
Bradley Steven Perry (Kaz) and Jake Short (Oliver) previously starred in 2 Disney Channel Shows, as Gabe Duncan in Good Luck Charlie (2010) and Fletcher Quimby in A.N.T. Farm (2011) respectively.
The superhero Titanio is a billionaire who fights in a futuristic metal suit, an homage to Iron Man. In fact, Titanio's suit resembles Iron Man's Mark 38 suit.