Tony Shalhoub's wife Brooke Adams makes her 5th and last appearance in the series after previously appearing as Leigh (the stewardess) in Mr. Monk and the Airplane (2002) (Season 1); as Mrs. Abigail Carlyle in Mr. Monk and the Kid (2005) (Season 3); as Sheriff Margie Butterfield in Mr. Monk Visits a Farm (2007) (Season 5); she reprised her role as Leigh in Mr. Monk's 100th Case (2008) (Season 7), and, lastly, she appeared in Mr. Monk and the Badge (2009) as the crazy "cat lady", Edith Capriani.
This is the third time that Joey Heatherton is mentioned. The first time was in Mr. Monk and the Panic Room (2004) and the second was in Mr. Monk Joins a Cult (2008).
Mark Harelik, who plays Mikhail Alvanov, also played "Davis Lynch" on Wings (1990) on which Tony Shalhoub had previously starred.