TLC goes into the lives of Jon, an Government I.T. Anaylist, and Kate, a part-time nurse, and their 8 children (franternal twins) Cara and Mady, age 5, and Alexis, Aaden, Collin, Hannah, Leah, and Joel (fraternal Sextuplets), age 16 months, as they struggle through the hardships and the joys of living central Pennsylvaina.