The episode was recorded on March 28 and April 4, 1990. Dave Coulier recorded alone on April 4, 1990.
"The Great Strazinski" was named by this episode's writer, Larry DiTillio, in tribute to former story editor J. Michael Straczynski. Straczynski previously named the character DyTyllio after Larry DiTillio in Ragnarok and Roll (1987).
When the Ghostbusters first examine the Magic Cabinet, Winston was supposed to be using the Specter Detector.
Two of the magician's assistants were scripted to be Carmen and Miranda but the scene involving them was discarded.
Egon and Ray were scripted to mention more theories but the scene was discarded.