The case trophies that Monk received at the end of the previous episode, "Mr. Monk and the Big Game," are missing from his mantle.
When Adrian goes to the police station to identify "the guy," an Asian woman comes walking around the corner straight towards him. The next second from a different angle she disappears.
When they put the pictures back on the mantel, Monk turns to the bookshelf. After the cut on Natalie, he's going to sit in the couch and the bookshelf is nowhere near the couch but behind Natalie.
When the fire engine leaves the firehouse and passes Eddie Murdoch on the street, it is obvious that it is a standard pumper engine. Yet, when it is seen parked outside Stefanie Preston's house in the summation, it clearly appears to be a vehicle of a different model.
At the hospital (just following the credits), when the doctor is checking Monk's pupil response, Tony Shalhoub's real iris can be seen contracting behind the blue and blood contact lenses that he is wearing.
[04:11] A close up of Mr. Monk's eye is shown. At first glance, the eye appears damaged to due to chemical burns, but when the doctor shines the light in Monk's eye, his natural irises can be seen around his constricted pupil through the center of the colored special effects contact lens.
During the alleyway scene, Stottlemeyer says that the house that burned down was just around the corner from the alleyway where Jake Colbert said he found the fireman's coat and helmet. Earlier, Stottlemeyer mentioned that the alley was in the Tenderloin District of downtown San Francisco. In the Tenderloin, there are SROs, not nice homes as shown in the episode. Similarly, the architecture of the buildings around the firehouse is not of a type seen in the Tenderloin. From the design of the building and the power lines around, the firehouse could more easily be placed in a different part of San Francisco, like the Sunset District.
When the engine pulls out of the firehouse to head to Stefanie Preston's house, it makes a right-hand turn onto the street. Then, when Eddie Murdoch is walking into the firehouse, he enters the building walking from the direction opposite from where the engine went. Yet, at the same time, the flashback shows the fire engine passing Murdoch on the street.
Many people have died in the series from softer blows to the head that Captain Stottlemeyer received.