The voice actors were recorded on November 14, 1986.
In the "The Real Ghostbusters Complete Collection", there is an Introduction to the episode by writer Michael Edens. He reveals he came up with the premise for the episode on a flight from Tennessee to Los Angeles.
The original title of this episode was supposed to be It's A Jungle Out There", but this was later changed. However, this original title is mentioned by Peter in the episode.
The title is a reference to the Betty Smith novel, "A Tree Grows in Brooklyn".
The business' name "Lorne's Greenhouse" is a pun and nod to Lorne Greene, best known as one of the stars of the classic Western television series "Bonanza".