The writer, Marc Scott Zicree, revealed that the inspiration for this story came from various "Twilight Zone" episodes where the characters go back to their hometown and things go awry.
The title is a reference to Thomas Wolfe's "Look Homeward, Angel," a 1929 novel and Wolfe's first.
This episode marks another appearance of Slimer's Stay Puft Marshmallow Man doll.
This is the only episode where Ray has a love interest, Elaine Phermon.
This is one of the few episodes that is about Ray Stantz and his love for Ghostbusting.