In a POV shot of the night club when Serpentor tells everyone that they fell right into his trap, the elevator doors are closed. As everyone heads to the elevator to evacuate the club, the doors are opened before they close up.
Although a virus can damage a computer, it cannot cause a computer to explode.
In space--and since neither of them is wearing a spacesuit--Leatherneck and Wet-Suit would die in two minutes or less. (Garbage bags cannot retain heat.)
The nightclub-turned-spaceship would be likely be damaged after re-entering Earth's atmosphere as well as crash-landing on Earth. Also, the occupants would likely be injured by the crash-landing.