After Bender is turned human, he is dressed in the same outfit as Homer J. Simpson from The Simpsons (1989), another show also created by Matt Groening.
After the Space Invaders spoof, Q*bert hops down the stairs and, while speaking backward, says, "where can a guy get some pants around here?"
The Rush song that Fry listens to during the Space Invaders segment, "Tom Sawyer", contains the lyrics "Today's Tom Sawyer, he gets by on you and the space he invades, he gets by on you." A clever little reference to both the band and the game that is being spoofed.
The "Professor Land fun bucks" that Bender steals from the Professor say "toxic ink" in the "Futurama Alien Alphabet".
D.U.I. Friday's is a reference to the restaurant chain T.G.I. Friday's.