In this episode Senator Richard Matheson is introduced, named after the great science fiction and horror writer of the same name.
The flight manifest that Scully is scanning in search for Mulder is a list of X-Files fans.
Not surprisingly, Mulder's computer password is "trustno1". These were the last words that Deep Throat said before he died, and was indeed used in the titles of the season 1 finale, The Erlenmeyer Flask (1994). "Trust No 1" would also be the title of an episode in Season 9.
According to producer Joseph Patrick Finn, it was a struggle for the show to make the Greater Vancouver area resemble the tropical island of Puerto Rico, and that "if you look closely you'll see pine trees in the back(ground)."