When Clark Kent is at Lex Luthor's mansion and walks in on Victoria Hardwick on her laptop in the library, the laptops screen says Cadmus on it. Cadmus labs is in charge of Project Cadmus which is a fictional genetic engineering project in the DC Comics Universe and has been in the extended DC universe in the DC TV shows and cartoons as well.
Tom Welling's locker-room scene marks the first time since the Pilot (2001)'s "scarecrow" sequence that he is seen without his shirt. He has no more "beefcake" scenes in the remainder of the first season.
In this episode, Chloe is saying that blue would suit Clark, a reference to his later Superman Suit which is mostly blue and red. In fact, Clark is wears mostly red and blue clothes during the series.
Amy Palmer's shrine for Lex Luthor features an article about the bank robbery from the episode X-Ray (2001).
The original story for the episode involved the sabotage of a school play, but was changed partially for reasons of time. The story as it was intended was published in the 2nd young adults Smallville novel See No Evil.