The concept of the Isotopes moving from Springfield to Albuquerque inspired the name change to the Albuquerque Isotopes (chosen in a poll by readers of the Albuquerque Tribune) of a real-life minor league baseball team when they moved from Calgary to Albuquerque in 2003. The ghost of Cesar Chavez comes to Homer. The Albuquerque Isotopes stadium is located on Avenida Cesar Chavez!
Bart says "Good Grief," Charlie Brown-style, when he sees Homer lying on top of a doghouse like Snoopy did in the Peanuts comic strip.
The salon that Marge walks out of is called Hairy Shearers. This is a joke on the name of cast member Harry Shearer who performs voices such as Burns, Skinner and Flanders.
The title is a reference to the Hasbro tabletop game Hungry Hungry Hippos.
Duffman's first name is revealed as Sid.