Stacey Fielding is a renowned pharmaceutical chemist who is apparently killed when the private airplane he was piloting crashed and burned. Prior to his departure, he had been drinking from a flask of whiskey his wife prepared for him and made an offhand remark that she would like nothing better than to see him dead. His wife, Miriam Fielding, hires Perry and Paul to check into her husband's alternate life, including checking out an apartment he had to look for $100,000 in missing funds. But all they find is an empty wall safe and the picture of his mistress, so Perry is concerned he's being set up. After the crash, Miriam Fielding is arrested and charged with murder. She hires Perry Mason to defend her but the forensic evidence doesn't support the charge and he manages to get her released only to have D.A. Hamilton Burger re-arrest her on the charge. Perry believes there's something else going on and can't help but think that the ongoing theft of pharmaceuticals from the factory has something to do with it.
—garykmcd