Ray Walston's character says they tried to force him to retire 10 years ago, and 10 years from now he'd still be there. Walston would pass away 4 months short of 10 years past the May 1991 air date; he died on January 1, 2001.
In the scene where Mikey Randall is making a new "Musso Highlights" video, in the far right monitor screen is a shot of Miss Musso from Episode 21; she is at her high-school reunion announcing the change in the program.
When Parker is leaving the dry cleaners--supposedly on the last day of school--poinsettias and garlands are clearly visible.
Lon Diamond and Clyde Phillips, the creators of Parker Lewis Can't Lose, make cameo appearances as themselves.
The characters of Ferris Bueller and Cameron Frye appear towards the end of this episode in a scene-within-a-scene.