The song Stewie sings over his growing fondness for his mother is "I've Grown Accustomed to Her Face" sung by Rex Harrison in My Fair Lady (1964). Coincidentally, Stewie's voice is based on Harrison.
Although this episode was released in season 2, it was made during season 1.
Randall Fargus is voiced by Dwight Schultz, who was one of the original characters in The A-Team (1983). Peter Griffin is a huge fan of the show and Family Guy spoofs it several times throughout its run.
Lacey Chabert's final voicing for Meg. Her schooling commitments and acting work were proving too much for her so she quit the show, to be replaced by Mila Kunis.