When the upstairs stripper at Fat Sam's is overheard talking to the factory worker, she is voiced by Sarah Fisher. However, when Larry talks to the stripper directly, she responds with a different voice - that of Natalie Berg.
When Larry operates puppets to cheer up Barbara Jo, she suggests they play quarters. Through the puppets, Larry responds, "Quarters?". Both Larry's real voice and Larry's puppet voice are heard saying this simultaneously, though this would be physically impossible for one set of vocal chords to pull off.
When in front of the bathroom mirrors at Lefty's Too, Spartacus and the D.I.O. frat house, Larry's reflection does not appear, though objects behind him can be seen.
Just before the Swingles Finals Talking Challenge, the word luscious is spelled 'lucious'.
The misspelling of the Library's sign as "Libary" is a deliberate joke indicating the quality of the education one is likely to receive at the college.
After you complete Charlotte's missions, if you talk to her one of the things she'll tell you is that you owe her a new pair of sandals. However, she wears army boots.