This is the third installment of the "Virtual Murder" series, renamed as "Murder Mystery". It follows the award winnings "Who Killed Sam Rupert?" and "Who Killed Elspeth Haskard?", and is followed by the award winning Who Killed Taylor French? (1994).
The Sheryl Lee material for "Who Killed Brett Penance?" and Who Killed Taylor French? (1994) was shot in May 1994, outside Santa Fe, New Mexico.
Lucie Fairwell, who is played by Sheryl Lee, was previously played by the creator of the "Murder Mystery" series Shannon Gilligan.