The "I Love A Mystery" films from Columbia were all based on a radio program of that name and each of them was made into very entertaining mysteries, the sort that Columbia was able to churn out on a tight budget with directors like Henry Levin.
This is the most gripping mystery in the batch, full of ingredients that will have you guessing from beginning to end just how all the loose ends will be tied up.
It starts off with the shrunken heads discovered when a plane crashes en route from California to Columbia, and then the plot includes a missing explorer who has possibly been murdered, an anxious wife afraid that someone is trying to kill her (MONA BARRIE), a young woman and her fiancé (ANITA LOUISE and MICHAEL DUANE)who resent being followed by detectives, and the detectives hired to cover the case (JIM BANNON and BARTON YARBOROUGH). Also in the mix: a restless black panther and the weird owner of a taxidermist shop (PAUL E. BURNS).
Nicely photographed in crisp B&W with appropriate set decorations, it has the look of a better than average programmer from Coumbia (not Republic, as another comment suggests).
Guaranteed to surprise and entertain, it's well worth watching.