Sort by Popularity - Most Popular Movies and TV Shows tagged with keyword "animal-experimentation"
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1. Rise of the Planet of the Apes (2011)
PG-13 | 105 min | Action, Drama, Sci-Fi
A substance designed to help the brain repair itself gives advanced intelligence to a chimpanzee who leads an ape uprising.
Director: Rupert Wyatt | Stars: James Franco, Andy Serkis, Freida Pinto, Karin Konoval
Votes: 570,535 | Gross: $176.76M
2. The Prestige (2006)
PG-13 | 130 min | Drama, Mystery, Sci-Fi
After a tragic accident, two stage magicians in 1890s London engage in a battle to create the ultimate illusion while sacrificing everything they have to outwit each other.
Director: Christopher Nolan | Stars: Christian Bale, Hugh Jackman, Scarlett Johansson, Michael Caine
Votes: 1,445,997 | Gross: $53.09M
3. Guardians of the Galaxy Vol. 3 (2023)
PG-13 | 150 min | Action, Adventure, Comedy
Still reeling from the loss of Gamora, Peter Quill rallies his team to defend the universe and one of their own - a mission that could mean the end of the Guardians if not successful.
Director: James Gunn | Stars: Chris Pratt, Chukwudi Iwuji, Bradley Cooper, Pom Klementieff
Votes: 383,834 | Gross: $359.00M
4. Avatar (2009)
PG-13 | 162 min | Action, Adventure, Fantasy
A paraplegic Marine dispatched to the moon Pandora on a unique mission becomes torn between following his orders and protecting the world he feels is his home.
Director: James Cameron | Stars: Sam Worthington, Zoe Saldana, Sigourney Weaver, Michelle Rodriguez
Votes: 1,390,108 | Gross: $760.51M
5. Resident Evil (2002)
R | 100 min | Action, Horror, Sci-Fi
A special military unit fights a powerful, out-of-control supercomputer and hundreds of scientists who have mutated into flesh-eating creatures after a laboratory accident.
Director: Paul W.S. Anderson | Stars: Milla Jovovich, Michelle Rodriguez, Ryan McCluskey, Oscar Pearce
Votes: 289,389 | Gross: $40.12M
6. The Fly (1986)
R | 96 min | Drama, Horror, Sci-Fi
A brilliant but eccentric scientist begins to transform into a giant man/fly hybrid after one of his experiments goes horribly wrong.
Director: David Cronenberg | Stars: Jeff Goldblum, Geena Davis, John Getz, Joy Boushel
Votes: 202,765 | Gross: $40.46M
7. Downsizing (2017)
R | 135 min | Drama, Fantasy, Sci-Fi
A social satire in which a man realizes he would have a better life if he were to shrink himself to five inches tall, allowing him to live in wealth and splendor.
Director: Alexander Payne | Stars: Matt Damon, Christoph Waltz, Hong Chau, Kristen Wiig
Votes: 125,213 | Gross: $24.45M
8. Deep Blue Sea (1999)
R | 105 min | Action, Adventure, Sci-Fi
Searching for a cure to Alzheimer's disease, a group of scientists on an isolated research facility become the prey, as a trio of intelligent sharks fight back.
Director: Renny Harlin | Stars: Thomas Jane, Saffron Burrows, Samuel L. Jackson, Jacqueline McKenzie
Votes: 142,867 | Gross: $73.65M
9. The Island of Dr. Moreau (1996)
PG-13 | 96 min | Horror, Sci-Fi, Thriller
After being rescued and brought to an island, a man discovers that its inhabitants are experimental animals being turned into strange-looking humans, all of it the work of a visionary doctor.
Directors: John Frankenheimer, Richard Stanley | Stars: David Thewlis, Marlon Brando, Val Kilmer, Fairuza Balk
Votes: 35,564 | Gross: $27.66M
10. Hollow Man (2000)
R | 112 min | Action, Horror, Sci-Fi
A brilliant scientist's discovery renders him invisible, but transforms him into an omnipotent, dangerous megalomaniac.
Director: Paul Verhoeven | Stars: Kevin Bacon, Elisabeth Shue, Josh Brolin, Kim Dickens
Votes: 138,703 | Gross: $73.21M
11. FernGully: The Last Rainforest (1992)
G | 76 min | Animation, Adventure, Family
The magical inhabitants of a rainforest fight to save their home, which is threatened by logging and a polluting force of destruction called Hexxus.
Director: Bill Kroyer | Stars: Samantha Mathis, Christian Slater, Robin Williams, Tim Curry
Votes: 34,066 | Gross: $24.65M
12. Jay and Silent Bob Strike Back (2001)
R | 104 min | Comedy
The comic "Bluntman and Chronic" is based on real-life stoners Jay and Silent Bob, so when they get no profit from a big-screen adaptation, they set out to wreck the movie.
Director: Kevin Smith | Stars: Jason Mewes, Kevin Smith, Amy Noble, Harley Quinn Smith
Votes: 161,288 | Gross: $30.09M
13. The Secret of NIMH (1982)
G | 82 min | Animation, Adventure, Drama
To save her ill son, a field mouse must seek the aid of a colony of rats, with whom she has a deeper link than she suspected.
Director: Don Bluth | Stars: Elizabeth Hartman, Derek Jacobi, Dom DeLuise, Arthur Malet
Votes: 45,359 | Gross: $10.14M
14. The Boys from Brazil (1978)
R | 125 min | Drama, Mystery, Sci-Fi
A Nazi hunter in Paraguay discovers a sinister and bizarre plot to rekindle the Third Reich.
Director: Franklin J. Schaffner | Stars: Gregory Peck, Laurence Olivier, James Mason, Lilli Palmer
Votes: 30,671 | Gross: $19.00M
15. Legally Blonde 2: Red, White & Blonde (2003)
PG-13 | 95 min | Comedy
Elle Woods heads to Washington, D.C. to join the staff of a Representative in order to pass a bill to ban animal testing.
Director: Charles Herman-Wurmfeld | Stars: Reese Witherspoon, Sally Field, Bob Newhart, Regina King
Votes: 72,990 | Gross: $90.19M
16. The Lawnmower Man (1992)
R | 108 min | Horror, Sci-Fi
A simple man is turned into a genius through the application of computer science.
Director: Brett Leonard | Stars: Jeff Fahey, Pierce Brosnan, Jenny Wright, Mark Bringelson
Votes: 39,149 | Gross: $32.10M
17. Alligator (1980)
R | 91 min | Horror, Sci-Fi, Thriller
A pet baby alligator is flushed down a toilet and survives in the city sewers. Twelve years later, it grows to an enormous size thanks to a diet of discarded laboratory dogs injected with growth hormones. Now, humans have entered the menu.
Director: Lewis Teague | Stars: Robert Forster, Robin Riker, Michael V. Gazzo, Dean Jagger
Votes: 15,968
18. Something the Lord Made (2004 TV Movie)
TV-PG | 110 min | Biography, Drama
A dramatization of the relationship between heart surgery pioneers Alfred Blalock and Vivien Thomas.
Director: Joseph Sargent | Stars: Cliff McMullen, Yasiin Bey, Luray Cooper, Alan Rickman
Votes: 15,455
19. Let the Right One In (2022)
TV-MA | 53 min | Drama, Horror
Follows a 12-year-old girl who lives a closed-in life after turning into a vampire, only able to go out at night. Her father does his best to provide her with the minimal amount of human blood she needs to stay alive.
Stars: Demián Bichir, Anika Noni Rose, Grace Gummer, Madison Taylor Baez
Votes: 5,860
20. Monkey Shines (1988)
R | 113 min | Drama, Horror, Sci-Fi
A quadriplegic man has a trained monkey help him with his paralysis, until the little monkey begins to develop feelings, and rage, against its new master.
Director: George A. Romero | Stars: Jason Beghe, John Pankow, Kate McNeil, Joyce Van Patten
Votes: 13,078 | Gross: $5.34M
21. Invader ZIM (2001–2006)
TV-Y7 | 24 min | Animation, Action, Adventure
An alien named Zim from the planet Irk is sent on a secret mission to conquer Earth, not realising that his leaders were just trying to get rid of him and hoped that he would die. Once there, Zim manages to disguise himself as a human child, but one boy named Dib sees through his disguise.
Stars: Andy Berman, Richard Steven Horvitz, Rikki Simons, Melissa Fahn
Votes: 22,661
22. Brainstorm (1983)
PG | 106 min | Sci-Fi, Thriller
Researchers develop a system where they can jump into people's minds. But when people involved bring their personal problems into the equation, it becomes dangerous - perhaps deadly.
Director: Douglas Trumbull | Stars: Christopher Walken, Natalie Wood, Louise Fletcher, Cliff Robertson
Votes: 13,172 | Gross: $8.90M
23. The Fly II (1989)
R | 105 min | Drama, Horror, Sci-Fi
The almost-human son of "Brundlefly" searches for a cure to his mutated genes while being monitored by a nefarious corporation that wishes to continue his father's experiments.
Director: Chris Walas | Stars: Eric Stoltz, Daphne Zuniga, Lee Richardson, John Getz
Votes: 24,758 | Gross: $20.02M
24. Project X (1987)
PG | 108 min | Comedy, Drama, Sci-Fi
An Air Force pilot joins a top secret military experiment involving chimps, but begins to suspect there might be something more to the mysterious "Project X".
Director: Jonathan Kaplan | Stars: Matthew Broderick, Helen Hunt, Willie, Okko
Votes: 12,871 | Gross: $18.53M
25. Fluke (1995)
PG | 96 min | Drama, Family, Fantasy
After a man dies in a car crash, he is reincarnated as a dog and attempts to reconnect with his family.
Director: Carlo Carlei | Stars: Matthew Modine, Nancy Travis, Samuel L. Jackson, Eric Stoltz
Votes: 7,472 | Gross: $3.99M
26. The Plague Dogs (1982)
PG-13 | 103 min | Animation, Adventure, Drama
Two dogs escape from a laboratory and are hunted as possible carriers of the bubonic plague.
Director: Martin Rosen | Stars: John Hurt, Christopher Benjamin, James Bolam, Nigel Hawthorne
Votes: 8,847
27. Primal Rage (1988)
R | 91 min | Horror, Sci-Fi, Thriller
A scientist at a Florida University accidentally creates a "rage virus" while conducting experiments to restore dead brain tissue in baboons. The virus soon spreads.
Director: Vittorio Rambaldi | Stars: Patrick Lowe, Cheryl Arutt, Sarah Buxton, Mitch Watson
Votes: 1,426
28. Man's Best Friend (1993)
R | 87 min | Comedy, Horror, Sci-Fi
A genetically engineered dog escapes from the science facility where it was created. A family takes it in unaware of its deadly instincts which soon emerge. The scientist who created the dog tries to find it before its too late.
Director: John Lafia | Stars: Ally Sheedy, Lance Henriksen, Robert Costanzo, Fredric Lehne
Votes: 4,908 | Gross: $12.97M
29. Dr. Jekyll and Mr. Hyde (1941)
Passed | 113 min | Drama, Horror, Sci-Fi
Dr. Jekyll allows his dark side to run wild when he drinks a potion that turns him into the evil Mr. Hyde.
Director: Victor Fleming | Stars: Spencer Tracy, Ingrid Bergman, Lana Turner, Donald Crisp
Votes: 9,891 | Gross: $3.92M
30. Snuff 102 (2007)
Unrated | 105 min | Horror, Thriller
A young reporter fascinated by the urban legend of snuff movies gets more than she bargained for when her deep research begins.
Director: Mariano Peralta | Stars: Andrea Alfonso, Julián Alfonzo, Rodrigo Bianco, Nicolás Blanco
Votes: 1,172
31. A Lizard in a Woman's Skin (1971)
Not Rated | 95 min | Mystery, Thriller
The potentially unhinged daughter of a British politician is accused of killing her hedonistic neighbor after she witnesses the murder in a dream.
Director: Lucio Fulci | Stars: Florinda Bolkan, Stanley Baker, Jean Sorel, Silvia Monti
Votes: 5,819
32. Unforgettable (1996)
R | 117 min | Drama, Mystery, Sci-Fi
A Seattle medical examiner uses an experimental memory transference drug to unravel the mystery surrounding his Wife's brutal murder.
Director: John Dahl | Stars: Ray Liotta, Linda Fiorentino, Peter Coyote, Christopher McDonald
Votes: 6,019 | Gross: $2.78M
33. Anti Matter (2016)
109 min | Horror, Mystery, Sci-Fi
A scientist faces the question of what makes us whole and if there is a part of us that is not part of this physical world when she discovers how to travel through a worm hole.
Director: Keir Burrows | Stars: Yaiza Figueroa, Philippa Carson, Tom Barber-Duffy, Noah Maxwell Clarke
Votes: 6,138
34. The Invisible Man Returns (1940)
Passed | 81 min | Drama, Horror, Mystery
The owner of a coal mining operation, falsely imprisoned for fratricide, takes a drug to make him invisible, despite its side effect: gradual madness.
Director: Joe May | Stars: Cedric Hardwicke, Vincent Price, Nan Grey, John Sutton
Votes: 5,332
35. Shakma (1990)
R | 100 min | Horror, Sci-Fi, Thriller
A group of medical students are attacked by an aggressive laboratory animal while competing in an after-hours role-playing game at their school.
Directors: Hugh Parks, Tom Logan | Stars: Christopher Atkins, Amanda Wyss, Ari Meyers, Roddy McDowall
Votes: 2,536
36. Retroactive (1997)
R | 91 min | Action, Crime, Drama
A psychiatrist makes multiple trips through time to save a woman that was murdered by her brutal husband.
Director: Louis Morneau | Stars: Jim Belushi, Kylie Travis, Shannon Whirry, Frank Whaley
Votes: 6,722
37. April and the Extraordinary World (2015)
PG | 105 min | Animation, Adventure, Comedy
It's 1941 but France is trapped in the nineteenth century, governed by steam and Napoleon V, where scientists vanish mysteriously. Avril, a teenage girl, goes in search of her missing scientist parents.
Directors: Christian Desmares, Franck Ekinci | Stars: Marion Cotillard, Marc-André Grondin, Philippe Katerine, Jean Rochefort
Votes: 8,465 | Gross: $0.29M
38. Deus Ex (2000 Video Game)
M | Action, Adventure, Drama
In a dark cyberpunk future where poverty, disease, oppression and terrorism are widespread, J.C. Denton, a new cybernetically-enhanced special agent, finds evidence of a massive conspiracy when his brother, also an agent, goes rogue.
Director: Warren Spector | Stars: Jay Anthony Franke, Brent Anderson, Ralph Barbagallo, Chad Bannon
Votes: 3,448
39. Gigantic (2008)
R | 98 min | Comedy, Drama, Romance
A mattress salesman's plan to adopt a Chinese baby is augmented by the arrival of a young woman who comes to his workplace, falls asleep on one of the beds, and upon waking starts to affect his life.
Director: Matt Aselton | Stars: Paul Dano, Zooey Deschanel, John Goodman, Edward Asner
Votes: 9,960 | Gross: $0.10M
40. Felidae (1994)
TV-MA | 82 min | Animation, Drama, Mystery
A cat must investigate brutal murders of other cats in a neighborhood he has moved into with his owner.
Director: Michael Schaack | Stars: Ulrich Tukur, Mario Adorf, Helge Schneider, Wolfgang Hess
Votes: 4,973
41. Carnival Magic (1983)
G | 86 min | Drama, Fantasy
A carnival magician with actual magic powers works with a talking chimp. The magician and the chimp soon become the stars of the carnival, drawing in big crowds. However, the wild-animal trainer decides to kidnap Alex and sell him.
Director: Al Adamson | Stars: Don Stewart, Jennifer Houlton, Howard Segal, Regina Carrol
Votes: 844
42. White Teeth (2002– )
240 min | Drama, Comedy
The lives of three families are woven together across three decades in multi-cultural Britain.
Stars: Om Puri, Phil Davis, Naomie Harris, Archie Panjabi
Votes: 780
43. The Story of Louis Pasteur (1936)
Passed | 86 min | Biography, Drama, History
The biography of the pioneering French microbiologist who helped revolutionize agriculture and medicine.
Director: William Dieterle | Stars: Paul Muni, Josephine Hutchinson, Anita Louise, Donald Woods
Votes: 3,161
44. The Monkey's Uncle (1965)
G | 91 min | Comedy, Family, Sci-Fi
A student is able to save Midvale College's football reputation using his radical invention.
Director: Robert Stevenson | Stars: Tommy Kirk, Annette Funicello, Leon Ames, Arthur O'Connell
Votes: 999
45. Tarzan in Manhattan (1989 TV Movie)
94 min | Action, Adventure
Tarzan goes to New York to rescue the chimp Cheetah, who has been captured by an evil animal experimenter. There, he teams up with Jane, a cab driver and daughter of an ex-cop private eye, who help Tarzan free Cheetah and his friends.
Director: Michael Schultz | Stars: Joe Lara, Kim Crosby, James Medina, Jan-Michael Vincent
Votes: 550
46. Trinity and Beyond: The Atomic Bomb Movie (1995 Video)
Not Rated | 92 min | Documentary, History, War
The history of nuclear weapons between 1945 until 1963.
Director: Peter Kuran | Stars: William Shatner, Edward Teller, W.H.P. Blandy, Frank H. Shelton
Votes: 3,624
47. Fear (1954)
84 min | Drama
Irene Wagner, the wife of prominent scientist Albert Wagner, finds herself blackmailed about her affair by her lover's jealous ex-girlfriend. The plot, an experiment in causing fear, drives her into a rage.
Director: Roberto Rossellini | Stars: Ingrid Bergman, Mathias Wieman, Renate Mannhardt, Kurt Kreuger
Votes: 1,784
48. Deus Ex: Invisible War (2003 Video Game)
M | Action, Adventure, Drama
Twenty years after Deus Ex (2000). Alex D is evacuated from Chicago to Seattle following a terrorist attack, and soon becomes embroiled in a network of plots as the world's factions fight for control of the world.
Director: Harvey Smith | Stars: Abigail Windham, Alexander Brandon, Bernadette Nason, Timeca M. Seretti
Votes: 856
49. The Animal People (2019)
Not Rated | 97 min | Documentary
A chilling portrait of what happens when activism rattles the institutions of power.
Directors: Denis Henry Hennelly, Casey Suchan | Stars: Steven Best, Heidi Boghosian, George W. Bush, Brian Cass
Votes: 294
50. Possible Worlds (2000)
93 min | Mystery, Sci-Fi, Crime
A man lives in parallel worlds, falling in love with the same woman, while the police hunt down a serial killer who steals brains.
Director: Robert Lepage | Stars: Tilda Swinton, Tom McCamus, Sean McCann, Gabriel Gascon
Votes: 2,155