- He and producer J.J. Abrams have often used actors from each other's TV/Film projects, sometimes resulting in the actors working on two projects at once. Examples are Kerri Russel on "Felicity" (1999) and "The Curve" (1998 and Michael Vartan "The Curve" (1998) and "Alias" (2001).
- He got his first big break in film in 1992, from famed producers Don Simpson and Jerry Bruckheimer.
- Partners with Academy-award winning composer Hans Zimmer and engineer and partner Jay Rifkin at Media Ventures Group.
- Frequently worked with stunt coordinator Jeff Imada and actor Bruce Lee's son Brandon Lee.
- Collector of contemporary art after having worked for Aron Spelling partner Douglas S Cramer.
- First feature length script bought by Jeffrey Katzenberg, co-founder of Dreamworks with David Geffen and Steven Spielberg for $1M.
- First TV series "Have Faith" was produced by actor-comedian John Ritter for ABC Television and Twentieth Century Fox, but was pre-empted from airing for 155 days by longest WGA strike in the guild's history. The comedy series preceded the ABC comedy hit "Rosanne" Both Lew and the creator and head writer of "Roseanne" Matt Williams were fired over creative differences and both went on to feature film careers.
- Developed the "Negative Man" for ABC television with Batman creator Bob Kane.
- Learned to play guitar watching high school alum Rusty Anderson who has been touring since 2001 with Beatles Paul McCartney.
- Frequently collaborates with Oscar® award nominee and documentary film maker Stuart Sender.
- Both hailing from Sunny Hills California, he and fellow screenwriter and Ironman 3 director Shane Black developed screenplays for Cliffhanger and Die Hard director Renny Harlin.
- Co-launched True Religion Brand Jeans. (July 2002)
- Developed comedy pilot with former Fox and USA Network prexy Stephen Chao based on single-life of fashion icon Vera Wang for the CW Network. (June 2008)
- Developed "untitled comedy pilot" for the CW Network with Chris Thomas creator of Tom Hanks comedy series "Bosom Buddies". (August 2008)
- Collector of contemporary art after having worked for Aron Spelling partner Douglas S Cramer. (March 2006)
- Jerome Lew and True Romance screenwriter Quentin Jerome Tarantino both worked for "Top Gun" director Tony Scott on "Crimson Tide.".
- Developed film and television projects with Lethal Weapon producer Jenny-Lew Tugend for Giants Co-owner Steve Tisch.
- Frequently collaborates with NY Times best selling "Finding Fish" author and screenwriter Antwone Fisher.
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