Formerly a close friend of Louis CK who appeared often on his show "Louie" and wrote the first 2 seasons of her series "Better Things" with him. After news of CK's sexual harrassment emerged in November 2017, Adlon cut ties with him and fired her former manager (who had also managed CK). In the runup to Season 3 of "Better Things", Adlon confirmed in a profile in The New Yorker that she had not any contact with CK in a very long time, and that she was trying to not mention or reference him during the show's production.