- One of the 36 founders of the Academy of Motion Picture Arts and Sciences (AMPAS)
- One of the most successful women screenwriters of her time, Meredyth began as a short story writer for various newspapers. She entered films in 1911 as an extra for D.W. Griffith at Biograph. She then moved to Hollywood and worked as both actress and a prolific contributor of scenarios. During the 1920's and 30's, she was under contract at most of the major studios, including MGM (1924-25; 1929-33), United Artists (1934-35), Warner Brothers and Columbia. She was famously brought in (along with Carey Wilson to replace June Mathis as scenarist for the blockbuster epic, Ben-Hur: A Tale of the Christ (1925).
- Third wife and widow of Michael Curtiz.
- Was one of the first woman to be nominated (though nominations that year were unofficial) for Best Adapted Screenplay at the Academy Awards. Both her nominated screenplays were the first screenplays adapted from novels to be nominated for the Oscars.
- Her first marriage resulted from a dare, after a high school football game. In his memoir, "Eighty Odd Years in Hollywood", her son John Meredyth Lucas claims it "may have been the shortest marriage in history".
- Son, with Wilfred Lucas, John Meredyth Lucas.
- Sister-in-law of David Curtiz.
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