- As he had so much respect for Marlon Brando and was afraid of working with him, all his scenes in Last Tango in Paris (1972) were shot on Saturdays, when Brando refused to work. Thus, they didn't meet together during the entire shooting.
- He played the same part - Antoine Doinel- in five films: as young boy in The 400 Blows (1959), as an adolescent in the "Antoine et Colette" segment of the anthology Love at Twenty (1962) and, together with the actress Claude Jade as his girlfriend, and later wife, Christine in Stolen Kisses (1968), Bed & Board (1970) and Love on the Run (1979).
- His performance as Antoine Doinel in The 400 Blows (1959) ("The 400 Blows") is ranked #98 on Premiere Magazine's 100 Greatest Movie Characters of All Time.
- In 1968, during the military dictatorship government in Brazil, as seen in the documentary Barra 68 - Sem Perder a Ternura (2001), Jean-Pierre Léaud, who was also a political militant, made a speech for hundreds of students at Brasília University, which is in Brazil's capital.
- Son of actress Jacqueline Pierreux and scenarist Pierre Léaud.
- Born on exactly the same date as Patricia Quinn of "Rocky Horror Picture Show" fame.
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