- Kyser organized his first band at the University of North Carolina in the mid-1920's. However, he came down with severe stage fright on his opening night, so that a friend -- the songwriter Johnny Mercer -- had to front the orchestra for the occasion.
- His mother was the first registered pharmacist in North Carolina.
- Kay Kyser's birthplace, Rocky Mount, North Carolina, was also the birthplace of modern jazz musician Thelonious Monk.
- 1990: Inducted into the Radio Hall of Fame.
- Bandleader and radio personality memorable for his "Kollege of Musical Knowledge". Often sporting his trademark mortarboard and gown, he appeared with his band in a few World War II-era movies.
- A devout Christian Scientist, he spent his last years appearing as a motivational speaker.
- Suffered from arthritis beginning in his forties
- He had three daughters: Kimberly Kyser (Kimberly Ann Kyser) was born in June, 1946; Carroll Amanda was born in 1948; Amanda Kay was born in November, 1952.
- He was awarded 2 Stars on the Hollywood Walk of Fame for Recording at 1708 Vine Street and for Radio at 1601 Vine Street in Hollywood, California.
- Radio/film personality
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