- On July 16th, 2010, Coulier rescued an elderly woman while riding his bike in Detroit, Michigan. The woman was walking into oncoming traffic and was nearly hit by a moped. Coulier grabbed the woman and carried her with one arm while riding his bicycle to safety.
- Introduced Candace Cameron Bure, then his co-star on Full House (1987), to hockey player, and her future husband, Valeri Bure at a charity hockey game.
- First lover of Alanis Morissette. They met at a celebrity hockey game and were together for a short time in the early 1990s. In a 2008 interview with the Calgary Herald, Coulier claimed to be the ex-boyfriend who inspired Morissette's song "You Oughta Know". Morissette, however, has maintained her silence on the subject of the song.
- Highly regarded for his voice-over talent, Dave's additional credits include many Saturday morning cartoon favorites. He started out doing voices on Hanna-Barbera's Scooby-Doo and Scrappy-Doo (1979) and the re-syndicated version of The Jetsons (1962). Dave then went on to lend his versatile voice to Jim Henson's Emmy Award-winning animated series, Muppet Babies (1984), where he portrayed Animal and Dr. Bunsen Honeydew for the run of the series, and then became the voice of three additional characters: Waldorf and Statler (the two old guys on the balcony on the original The Muppet Show (1976)) and Bean Bunny. Additionally, Dave also voiced the character of Peter Venkman on The Real Ghostbusters (1986) cartoon (played by Bill Murray in the movies).
- Boasts his comedy routine is clean (without any four letter words) but also states that it isn't as wholesome as Full House (1987).
- Coulier is pronounced "Cool-Yay".
- Has a great passion for playing hockey. He is a member of the Celebrity All-Stars squad whose team includes Jason Priestley, Matthew Perry, Alan Thicke, Michael J. Fox, Michael Keaton, and Richard Dean Anderson.
- His famous tag line "Come on now, cut-it-out!", complete with hand motions that he became known for during Full House (1987), was actually created before he did that show. He invented the saying while he was on the variety show Out of Control (1984) on Nickelodeon in 1985.
- He has said he is the person Alanis Morissette is singing about in her song "You Oughta Know".
- Imitated various celebrities throughout several episodes of Full House (1987), including Bill Murray, Bob Hope, Walter Brennan, Bill Cosby, Paul Reubens (as Pee-Wee Herman), and Joe Pesci.
- Still close with his Full House (1987) cast mates, in particular Candace Cameron Bure, whom he introduced to Valeri Bure, NHL star of the Florida Panthers and the Dallas Stars, who became Cameron's husband.
- Has a son, Luc, born in late November 1990, with ex-wife Jayne Modean.
- A Detroit native, is a huge Red Wings fan, and wore Red Wings jerseys on some episodes of Full House (1987).
- Plays guitar, harmonica and piano.
- Attended game 3 of the 1989 NBA Finals at the Great Western Forum but was booed by the Laker fans because he was wearing a Detroit Pistons shirt.
- Parents are Dave and Arlen (Arlen passed away as mentioned in Fuller House premiere), grandparents are Theodore Coulier (1892-1971) and Miriam Coulier (1901-1998).
- Is often confused with actor Jeff Daniels. On Twitter he posted: "Sorry, Jeff Daniels is already my doppelganger.".
- Owned a dog named Heckler during his Full House (1987) career.
- Partnered with former Olympic skater Nancy Kerrigan on the TV show Skating with Celebrities (2006).
- Dave, Lorenzo Music, and Bill Murray are connected to the same role: Bill Murray played Peter Venkman in the movie Ghostbusters (1984) while Music started off as the voice of Peter in the cartoon The Real Ghostbusters (1986) and Coulier took over the voice duties from Music. Coulier also imitated Murray on a few episodes of his show Full House (1987).
- He used to cut school and go to Tiger games at old Tiger Stadium with friends.
- He attended the University of Michigan but dropped out after his freshman year to pursue comedy full time.
- He's an avid fan of the Detroit Tigers and wore several Tigers throwback jerseys on Full House including a Tigers old English "D" cap.
- His children's entertainment company, F3 Entertainment, was founded in early 2001.
- Is a long-time friend of Anchor Bay High School English instructor Christopher LaMilza, with who has played hockey in the past.
- His father was of one half Belgian Flemish, one quarter German, and one quarter Slavic, descent. Dave's mother was of French-Canadian heritage.
- Currently hosting Animal Kidding (2003) on Animal Planet. (2003)
- Co-starring on VH1's The Surreal Life (2003) third season. (September 2004)
- Currently starring in the film Shredderman Rules (2007) for Nickelodeon (2007)
- Rumor's Comedy Club - Winnipeg, Manitoba, Canada (November 2001)
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