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- DirectorMimi LederStarsAnthony EdwardsGeorge ClooneySherry StringfieldThe ER staff's slow snow day becomes chaotically hectic when the casualties of a 40 car traffic accident flood in.
- DirectorRod HolcombStarsAnthony EdwardsGeorge ClooneyNoah WyleThe pilot for the popular TV series is set during 24 frantic hours in the lives of a group of doctors, nurses, and staff members of a busy emergency room at a Chicago hospital. They deal with the seemingly endless casualties that stumble into their place of employment. The central characters are the chief resident and family man Dr. Mark Greene, who is considering a job in private practice due to pressure from his demanding law student wife Jennifer; outgoing Dr. Doug Ross, who deals with cases in his own personal way; straight-arrow Dr. Susan Lewis, trying to get by another long 36-hour shift; inexperienced third-year med student John Carter; cocky surgical resident Dr. Peter Benton; and troubled chief nurse Carol Hathaway.
- DirectorMimi LederStarsAnthony EdwardsGeorge ClooneySherry StringfieldDr. Benton has to deal with the aftermath of his mother's fall and crosses the line with the surgical attending when he insists on scrubbing in for her operation. Dr. Greene deals with Jodi O'Brien who is two weeks away from giving birth. With the obstetrics attending unavailable, he decides to try to deliver her baby in the ER, with tragic results.
- DirectorChristopher ChulackStarsAnthony EdwardsGeorge ClooneySherry StringfieldDoug saves a kid who's stuck in a flooded culvert and becomes a local hero when a TV helicopter films part of the rescue operation.
- DirectorChristopher ChulackStarsAnthony EdwardsGeorge ClooneySherry StringfieldMark Greene strikes a deal with Kerry Weaver - he will support her application for an ER attending position if she in turn will support Susan Lewis for Chief Resident. When Susan doesn't get the job, Mark is told to go ask her why. Carter is finally going to graduate and wants Benton to attend the party his family is throwing for him. Unfortunately, Carter decides to sit with a young patient awaiting a liver transplant and misses his own graduation ceremony. With the news she has received about her former husband Al's health, Jeanie Boulet decides to have herself tested. Doug Ross' girlfriend Karen forges his prescription for percodan. Hathaway's boyfriend, Shep, is refusing to undergo his anger management treatment. Mark's ex-wife Jen tells him that she is going to re-marry. Loretta Sweet asks Greene if he would become guardian to her kids.
- DirectorMimi LederStarsAnthony EdwardsGeorge ClooneySherry StringfieldShep and Raul go in a burning house without the proper equipment to save three children.
- DirectorLance GentileStarsAnthony EdwardsGeorge ClooneySherry StringfieldMark has to work for the fourth night in a row while a lot of the staff are absent and the number of patients is towering.
- DirectorAnthony EdwardsStarsAnthony EdwardsGeorge ClooneySherry StringfieldSusan has therapy to get over losing little Susie and Jeanie's ex-husband is brought in.
- DirectorJacque Elaine ToberenStarsAnthony EdwardsGeorge ClooneyNoah WyleCarter feels guilty about Gant's death. Benton doesn't want to talk about it.
- DirectorChristopher ChulackStarsAnthony EdwardsGeorge ClooneyNoah WyleNurse Carol Hathaway is held hostage during a convenience store robbery, then befriends one of the gunmen.
- DirectorChristopher ChulackStarsAnthony EdwardsGeorge ClooneyNoah WyleAnspaugh is furious when Carter tells him he wants to quit surgery. Charlie is brought in with an overdose. Mark keeps struggling with his beating.
- DirectorRod HolcombStarsAnthony EdwardsGeorge ClooneySherry StringfieldDoug's one-night-stand has a seizure and he brings her to the ER.
- DirectorAnthony EdwardsStarsAnthony EdwardsGeorge ClooneyNoah WyleBenton and Elizabeth Corday spend the night together. Corday is shocked when Robert Romano suggests that they go out on a date. John Carter and his grandmother clash over the future of Chase Carter; she wants him cared for at home while John feels he should remain institutionalized where he can continue to receive therapy. Carol Hathaway finally gets around to inviting her mother to a Sunday brunch with her and Doug but is a bit surprised when she shows up with her boyfriend. In the ER, Hathaway comforts a man who is going to die from chemical burns.
- DirectorChristopher ChulackStarsAnthony EdwardsGeorge ClooneyNoah WyleBecause of benzene that's been spread, the ER has to close. Weaver gets felled and Carter has to take the lead.
- DirectorSarah Pia AndersonStarsAnthony EdwardsGeorge ClooneyNoah WyleMark treats an old lady who has been brutally raped. Carter's grandmother visits Carol's clinic. After he's touched by Benton, a blind man can see again!
- DirectorChristopher ChulackStarsAnthony EdwardsGeorge ClooneyNoah WyleRoss and Greene travel to a near-deserted stretch of California to investigate circumstances surrounding a death in Doug's family.
- DirectorJohn WellsStarsAnthony EdwardsGeorge ClooneyNoah WyleDoug faces possible criminal charges after Ricky Abbott dies when Ross shows Joi how to give Ricky a lethal dosage of medication. Doug is delegated to desk duty, Carol's clinic is shut down for acquiring the P.C.A. machine for Ricky, and Greene and Weaver face future disciplinary action for not reporting Doug's earlier mistakes. Meanwhile, Carter and Lucy discover a mutual attraction, Benton studies with a sign language instructor, and Romano begins his first day as acting ER chief.
- DirectorChristopher ChulackStarsAnthony EdwardsGeorge ClooneyNoah WyleA man arrives at the ER with his gravely-injured daughter then runs out, presenting a critical situation because he's the only match for her blood type. While Carter and Lucy alternately bicker and work well together as they try to track down the father, blood-supply snafus spur Benton to perform an unprecedented operation on the girl.
- DirectorJonathan KaplanStarsAnthony EdwardsNoah WyleJulianna MarguliesBenton travels to a Mississippi clinic during his vacation time to earn money for his son's therapy, and becomes a local hero when he uses his medical knowledge to help several residents.
- DirectorChristopher MisianoStarsAnthony EdwardsNoah WyleJulianna MarguliesOn Thanksgiving Day Carol goes into labor. She's able to get to the ER only thanks to Luka's help. She delivers the first baby in the ER, but the second causes some trouble. Greene leaves Elizabeth to deal with his father and daughter, as he rushes to assist Carol.
- DirectorLaura InnesStarsAnthony EdwardsNoah WyleJulianna MarguliesDr. Greene and Dr. Corday bond with their parents, Lucy cares for a patient with a psychotic break, and Valentine's Day celebrations in the ER end tragically.
- DirectorJonathan KaplanStarsAnthony EdwardsNoah WyleJulianna MarguliesCarter and Lucy are discovered and the staff struggles to save them and go on with normal patient care.
- DirectorJohn WellsStarsAnthony EdwardsNoah WyleJulianna MarguliesGreene prepares to bury his father. Chen worries about Carter's mood swings. After witnessing the interaction between a dying woman and her family, Hathaway realizes she wants her family together and flies to Seattle to join Ross.
- DirectorDavid NutterStarsAnthony EdwardsNoah WyleLaura InnesMark Green is in New York on New Years eve for cancer surgery. Meanwhile a father and son are involved in a car crash.
- DirectorJonathan KaplanStarsAnthony EdwardsNoah WyleLaura InnesIn the series' 150th episode, a massive train wreck mobilizes the emergency room doctors. Corday, Carter and Kovac rush to the scene. Corday falls and injures her back, bringing on contractions in only her 25th week of pregnancy. While amputating the legs of a fallen firefighter, Corday stops because of her pain.