14th century France, Amicia and her little brother Hugo are on the run from the Inquisition's soldiers and survive during their emotional journey unstoppable swarms of rats from the Black Plague.
After escaping their devastated homeland, Amicia and Hugo travel far south. There, they attempt to start a new life and control Hugo's curse. But, when Hugo's powers reawaken, death and destruction return in a flood of devouring rats.