Two neighbors form a strong bond after both suspect extramarital activities of their spouses. However, they agree to keep their bond platonic so as not to commit similar wrongs.
A teenage girl, overjoyed when her favorite uncle comes to visit the family in their quiet California town, slowly begins to suspect that he is in fact the "Merry Widow" killer sought by the authorities.
On a journey to find the cure for a Tatarigami's curse, Ashitaka finds himself in the middle of a war between the forest gods and Tatara, a mining colony. In this quest he also meets San, the Mononoke Hime.