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- The work and lives of doctors and nurses in a Spanish hospital.
- Based on true events, the movie tells a story of fraternity and friendship between teenage girls, students of a private college, and the unexpected reaction of the group to the premature pregnancy of one of them.
- The story of Juan Carlos de Borbón, from his parents sending him to study in Madrid at the age of 10 until he became King of Spain and announced free elections, bringing democracy back to the country.
- Justino was working in a bull-ring but now he is retired. For him it is very difficult to adapt to the new situation although he will find soon a hobby without forgetting his profession.
- David, a humble boy, is signed by the quarry of a first division soccer team. The arrival of this young talent threatens the captain, Alex, so he will try to put David aside from the team by all means. They fight in and off the field of play. In the quarry, they will discover a world of rivalry, love, friendship and betrayal.
- It's Esther and Maca's wedding day. Esther spends the day with her mother and her cousin, who is also her hairdresser, and receives the special visit of her grandmother. Maca also receives a visit, from her and Teresa's ex-girlfriend Azucena. Also, her parents finally agree to attend her wedding. All of their hospital colleagues go to the wedding except Rusti, whose daughter is ill at the hospital; Cruz, who has no babysitter for her daughter; Carlos, who forgets about it; and Laura, who goes but sees Belén and Javier kissing and with their baby, and returns to the hospital, where she meets Carlos and they decide to have dinner together. Begoña sells the guard in order to be able to go to the wedding. Before, has asked Dávila for help, but he had said he couldn't do anything. Aimé decides not to accept the job in Belgium but to continue working at Central. Laura ends the residence in 3 months and has begun to sell curriculum to other hospitals.
- Héctor has a place in the hospital due to Vilches' negotiations. Meanwhile, Vilches' operation is successful in the beginning but he suffers a bruise afterwards and slips into a coma, and Teresa gives Cruz the video. Guillermo doesn't accept Vilches' situation and escapes, but Alejandro makes him see that his attitude is wrong. Candela doesn't like the idea of having Alenjandro and especially Guillermo living with her and her mother. A SAMUR member is one of the dead when a flat is demolished; another one, Mauri, is in the hospital recovering from Begoña using a wrong bag of blood on him. Maca's patient Jaime dies during his operation and she feels guilty. Gabriela is in hospital for her last chemotherapy session. Dávila wants to talk with Héctor to find out if his relationship with Gabriela is serious. Miguel, Mari Ángeles' boyfriend, is violent and hits her when he notices that Mari Ángeles went with Nuria to the same hospital where her ex-husband Aimé.
- Vilches and his mother continue to worry about Alejandro, who is still depressed, and Andrea tries to help them. Teresa will be interviewed by a friend's daughter, but she discovers Elisa's story and finally decides to interview her, stirring up Teresa's jealousies. Esther has a date with an apparently-perfect man, but she is already in love with Rusti, who continues to plan his wedding with Queca. Cristina tells Santiago about her infidelity with Raúl and he decides to end their relationship. Laura wants to live with Javier, but they don't agree about where.
- A man walks into the hospital nursery with a bomb on his chest and demands to speak with Dávila. It will blow up in 60 minutes if they don't perform a surgery on his son.
- Dávila invites Elisa to spend a weekend in Amsterdam with him. Javier has invested a great deal of money and Laura is worried that he risks too much; she also tells him that she came back from Boston because she missed him. Nacho has decided to leave his work as designer because he isn't interested in it anymore, but Fran doesn't agree with his decision. Santiago had a dinner with Cristina, but hadn't forgotten that he also had a meeting with Prada, so Christina profits by this double-booking with Raúl.
- A woman in a clinic for liposuction suddenly develops complications. When the patient dies, her husband denounces the clinic, which turns out to be owned by Javier's father. Andrea's father joins the hospital after an attempted suicide. Elisa has a breast tumor and the treatment is incompatible with her pregnancy, but she postpones chemotherapy.
- Vilches tells his partners that has cancer and must be operated on; Cruz, who had bought a new portfolio, finds the tests in the old one. It's confirmed that Fran isn't returning, and a new doctor, Rober, is assigned to the SAMUR unit. Eva, who had occupied the place, thinks that Rober has been appointed to the post through influence and has a tense relationship with him. Javier and Belén want to have a baby but she does not manage to remain pregnant, so they run fertility tests. Laura is angry with Javier when she realizes that her ex told his wife intimate details of her past relationships. Héctor's daughter has varicela (chickenpox), which cancels her visit to Spain. Maca's birthday approaches and Esther doesn't know what gift to give her so she seeks "informers" who might have ideas. Mari Ángeles wants her new partner Miguel to meet Nuria, so she asks Aimé to let her spend some time with them.
- Andrea gives Raúl his evaluation and it's not very positive. Cristina presents her resignation to Aimé but doesn't explain the reason, so the director of Urgency asks her about it; finally, Santiago talks with the psychiatrist and she changes her mind. Esther tells Rusti that has a new boyfriend although they have just begun the relationship, later Elisa asks her about him and Esther confesses that this person doesn't exist. Later, Rusti, who has been in love with Esther for years, knows about it and they have sex although Rusti is now with Queca. Javier and Laura are looking for a flat to share; when she mentions this to an old, dying patient, he decides to give them his house in gratitude for Laura's kind, affectionate treatment. Fran notices that Nacho fancies Eva, but thinks that his brother has no chance with the SAMUR nurse.
- Maca sees Esther walking to work and offers to take her there by motorbike. They are becoming good friends and Teresa notices it. Javier starts to treat Laura better, and she has just met Aimé's daughter Nuria. It's Cruz's birthday and her daughter goes to the hospital to felicitate her, then has the Physics class with Héctor and asks him to take her to the bank to pay for her English classes. There is a dangerous attraction between them. Vilches invites Cruz to have dinner with him during the weekend. He also asks her about the conference, obviously unaware that she spent the night with Dani, one of the medical students. Mercedes comes to the hospital again and Maca discovers that she has Munchausen syndrome: wanting to make her daughter and grandson unwell so she can take care of them. Dávila and Elisa are continuously arguing since she found out that her son is coming to Spain. She wants to make many changes in their flat to adapt to the new situation, and Dávila recognizes that he is a bit jealous. His unusual bad humor makes him argue with many people at the hospital.
- Fran participates in the selection of firefighter without telling Eva, because he wants to show his enemy Jero that getting his job isn't difficult and he'd have no problem getting it. Guillermo must go to a new family and Vilches hasn't told him, while Cruz works out the days Candela would spend with her and the ones she'd spend with her father after the divorce. On the way to attend childbirth class with Queca, Rusti gets trapped in an elevator with two people and the dangerous dog of one of them. Laura continues her parallel relationships with Javier and Aimé and doesn't know what to do when the latter asks her to make a decision. Héctor, who knows the situation, tells her that doing well results impossible.
- Laura and Javier are not together anymore and he tells her that he knows about her infidelity with Aimé. Now she doesn't know whether to keep seeing Aimé or not. Javier has a free day to go see a rally in which a friend is participating, and there he sees again his friend's sister Marta, who looks completely different; he didn't even recognize her. Fran and Eva are also at the rally and must attend an important accident. Later in the hospital, Javier and Laura are having a tense conversation when Marta, who is with her injured brother in the hospital, kisses Javier. Guillermo has been missing for a week when the SAMUR members find him; he is angry with Vilches, but finally forgives him and returns home. Cruz operates on an obese patient whose doctor doesn't take care; when the man dies, she feels guilty until Vilches makes her see that it wasn't her fault. Esther is expecting the new nurse and when new pediatrician Maca arrives, she thinks she's the new nurse, which doesn't begin their professional relationship in the best way.
- Candela has pneumonia and Cruz scolds her for not wrapping herself up warmly in winter; she also finds cigarettes in her jacket. Dávila continues to do tests on Vilches, who is feeling unwell. Cruz notices Vilches acting very strangely towards her. Laura has left Aimé and wants to collect her things from his house. Héctor wants to keep working at the hospital and asks the others for help, but it's doubtful that he can have a place; he phones Gabriela but the chemotherapy is making him feel so ill that he doesn't ask. A new 40-year-old resident, Mabel, arrives in the hospital. On the street the SAMUR unit finds a beggar from Sevilla; he has no health problems, but Salva wants to bring him to the hospital so he can have a place to spend the night, but Eva is against it. Laura moves in with Eva to take Fran's place in her flat. Maca gives Esther a makeover after a patient calls her ugly.
- Aimé finds out that Miguel hits Mari Ángeles and decides to end the situation by going to talk with him, but they have a fight and Aimé punches Miguel. Maca stays obsessed with Jaime's death and receives Dávila's complaints because of the increase in the Pediatrics expense because of the numerous tests to which she submits patients. In addition, Héctor is obliged to investigate a disease that he does not know before the diagnosis that Dávila gives one of his patients. Regardless, a newly-released attached doctor will need to hurry in his intention since the patient, who suffers constant headaches, is not responding to treatment. Vilches has decided to live with Cruz, and they gather their children in the hospital to let them know, but the doctor's daughter Candela does not arrive.
- Mario is still missing and Vilches and Lucas try to discover what has happened while Diana assures them that Gonzalo is alive. Prada presses Santigo to reduce expenses and Aimé feels controlled by the hospital's director and tells Javier that Laura has asked for a scholarship to finish her residency in the USA. Andrea isn't sure about her future with Seró, because he is never available when she needs him because of his wife and daughter. Elisa tells Teresa that she is thinking about asking to have her hours reduced. She feels that she is spending little time with her daughter Elena and missing important moments in her life. Cristina tests Mariano and determines that it is better if he leaves Urgency, but Rusti doesn't share her opinion. Fran, a new doctor, arrives at the hospital and becomes implicated in the case of a delinquent child.
- Andrea is obsessed with Raúl and feels unable to overcome what happened with him; Santiago asks Cristina to make an informed decision about the resident. He is surprised when she verifies that the psychiatrist thinks that Raúl is not a psychopath and is unlikely to become one in the future. Rusti avoids Queca after his infidelity with Esther, who is very disappointed because she thinks that Rusti is going to split with his fiancée and begin a relationship with her. Nacho suffers strange attacks and Fran wants to carry out a toxic analysis to see if he has drugs in his system. Eva thinks that the doctor is very hard on his brother but finds out later that Nacho has epilepsy. Laura and Javier have problems with a neighbor who snores; they operate on him, but later discover that they might not spend many more nights in their new flat: the niece of the man who gave it to them claims that it belongs to her. Aimé's ex-wife arrives in the hospital, she had alcohol while taking pills, putting her life in danger. Vilches' son tries to commit suicide.
- Cruz receives Vilches' condolences for her son's death while she and her husband are considering divorce, preferring to postpone rather than make the situation worse for Candela. Esther's petition is denied but she hasn't changed her mind and thinks that she is a good boss, able to do that work as well as Elisa. Laura, who is investigating the listeria outbreak in the hospital, and Aimé kiss. Her relationship with Javier is not going well at the moment; he wants her to go to a dinner organized yearly by his father for the anniversary of their private clinic, but she has a previous commitment with her brother. Sofía, the Argentinian woman Héctor married to legalize her situation, tries to commit suicide because she has a relationship with a married man who doesn't want to break up with his wife. She tries to get back with Héctor, but he is still in love with her and prefers not to see her anymore.
- A gas leak provokes confusion in a battered-women's center with the result of two internal wounds that they are deposited in the Central. One of them, beside showing signs of recent mistreatment, is pregnant; the other one wants to see her husband. Javier and Laura attend to a fruiterer who has been punctured by an exotic spider upon opening a box that came from Brazil. In opposition to what the doctors think, the patient believes that he is dying and decides to be honest with his family. Héctor continues to mentor students Ana and Raúl's guardianship; they are now analyzing an Argentinian who insists that he knows the doctor, but he does not remember of what. Amador, the patient, has damaged lungs, and it is Ana, not Héctor, who succeeds with the diagnosis. At night Héctor, who isn't in his best moment, has dinner with Eva and they spend the night together. Gabriela hears a conversation in Central's cafeteria and notices the relationship between her father Dávila and Begoña. Finally, Carlos and Laura prepare the trip to Guatemala, but despite the fact that they have it calculated for one month, the unforeseen always arises to foil plans. One of these unexpected misadventures provokes that Laura must solve a problem immediately and leave a patient with a stomach-ache and when another doctor comes, the patient has disappeared. Finally, Carlos is stabbed and Javier leaves for Guatemala with Laura. Vilches tries to reduce Cruz's workload.
- Andrea tells Santiago that Cecilia won't allow her to assume responsibilities, so he gives her the case of a woman with a stomach-ache. Unaware that her patient is pregnant, the resident makes a mistake when she asks Rusti to prepare the patient for a radiography. Susana's date with Mario is pre-empted by her mother, who seems to invent illnesses in order to reclaim her attention; Mario tries to meet with her again. Esther and Leonor have their first problems as flatmates, while the SAMUR ambulance is stolen with Diana, Diego, and Mario inside. Javier has a patient who has problems with an intervention that was made in his father's clinic.
- Elisa's son Alberto arrives from Boston with a surprise: his girlfriend Jasmine comes with him. He tells his mother that he doesn't feel well, but "forgets" to tell her about his farewell party. This angers Dávila, who makes a diagnosis then realizes that the patient just has a major hangover. Héctor has problems with Candela. Maca invites Esther to her house while Javier continues to make Laura's life miserable. Vilches is jealous of Dani and doubts Cruz in a case; the autopsy gives her the reason, but she receives death threats from the dead patients' relatives. Eva's father, who has Alzheimer's, climbs to the roof of his house and almost throws himself off it.
- Cruz is going to take maternity leave, but is still working and doesn't feel well, so she goes home--where she finds Guillermo and Alejandro with their girlfriends. Cruz begins to have contractions and the boys help her until Eva and Rober arrive with the ambulance; finally she gives birth to daughter María. Maca's father Pedro will be operated on at the hospital and Esther doesn't feel comfortable; Pedro and Amparo, Maca's mother, disapprove of Esther and Maca's relationship and future marriage, and each parent treats their daughter's partner coldly. Héctor sends flowers to Gabriela, but she doesn't accept them or forgive his infidelity. Héctor confesses to Laura that he spent the night with another woman and, although he doesn't name names, she guesses that it was Eva. Laura she spent Laura and Javier continue to see each other, but she asks Javier to leave Belén. Begoña wants to go living with Dávila, but he thinks it's still too soon.
- The media phones constantly asking for Santiago, who has left the hospital. The new director hasn't been decided upon and the hospital is working with many difficulties. Fran doesn't want his relationship with Eva to be public, but Eva doesn't agree and wants to tell Nacho. Later, Nacho tells Eva that he got a job in Barcelona and suggests that she go there with him and they live together. Leonor, Javier's ex-girlfriend who was a nurse at Central until she left when they broke up, is spending a few days in Madrid and visits the hospital, awakening Laura's jealousy. Cruz and Vilches have their first argument as doctor and boss of the operating rooms. Queca announces to Rusti that they are expecting their first child.
- Maca has a very cordial relationship with the policewoman who investigates the injuries of a kid who is in the hospital and Esther is jealous. Javier is on his honeymoon with Belén in the Caribbean and sends a postcard that is seen by Aimé and Laura. Aimé is waiting for Cruz at the airport for their trip to Lisboa, but just when she is leaving the hospital, a patient arrives that keeps her from getting to the airport on time.
- Dávila's health is very complicated and Esther substitutes Elisa as boss of nurses because she wants to spend more time with him. Santiago continues to investigate Los Abedules and Prada offers him money to be quiet and not continue. Laura and Javier have an argument because his mother mentioned the possibility of a wedding between them. Vilches and Fran must make a report together, but they don't agree. Sofía asks Héctor to marry him so she can continue to live in Spain.
- Ferreira leaves the hospital and proposes that Santiago take his place. Diana is not concentrating on her work and makes serious mistakes. Mario tries to protect her and talks with a policeman friend to find out if the nurse is part of a sect. Elisa is worried about her baby and must decide whether to be operated on for her tumor before or after giving birth. Cristina doesn't like Santiago's attitude and doesn't want to continue hiding their love. Juan has left Esther and she doesn't know where he is, Rusti wants to help her, but the nurse has decided to accept her ex-boyfriend's decision. Laura observes Javier from a different perspective as he tries to show her that he is a good person. The case of an asylum where elder people were abused makes Andrea worry about her father.
- Esther tries to convince devastated Maca that Jaime's death is not her fault. She feels incapable of telling the relatives of the children she attends that they won't die. Vilches comes out of his coma and asks Cruz to marry him, but she thinks they should live together first. Héctor gives a glass in order to celebrate his place and Vilches' recuperation. At the party, Javier takes Laura aside, proposes that they leave the hospital together, and kisses her; Maca drinks too much and talks badly to Esther, who doesn't know how to help her partner. Eva wants to change of SAMUR unit because the relationship with Rober doesn't improve, but he thinks they'll get on together eventually. Cruz returns the video to Teresa and asks her not to tell Vilches that she watched it. Aimé diagnoses malaria with a incredible and apparently unrealistic story, but Dávila finishes by accepting that the doctor had a reason. Aimé's ex-wife has not seen their daughter in a week and he sees in her face that her new boyfriend is abusing her. Dávila meets Begoña at Héctor's party and is interested in the fact that she doesn't integrate with her partners.
- During a photographic session, a model falls on a mirror and destroys her face. There is no aesthetic surgeon at Central who can help her, so they summon Joaquín Sotomayor, Javier's father. Joaquín agrees on the condition that his son and Leonor help him during the intervention. The operation is a success and Joaquín offers to employ Javier and Leonor with him at the private clinic. Javier refuses, but Leonor believes that she should think it over.
- Vilches is working at the hospital and also in a private clinic; he's exhausted and making mistakes that are uncharacteristic. Elisa has decided to have a child alone, which is very difficult for Santiago to understand. Esther goes to Juan's house to assist him but the patient thinks that he's receiving a public sanitary service. Andrea is intimate with the married Seró. Javier receives his first resident, a young doctor called Laura.
- Mario and Diana achieve that a boy recovers the sight after having drunk from a drink a liter of rum and Coca-Cola. But, to a little time, several of his companions enter afflicted by alcoholic intoxication.