- Step-daughter of Billy Ray Cyrus, who adopted her after marrying her mother.
- Older sister of Trace Cyrus.
- Older of 2 children in family of Baxter Neal Helson & Tish Cyrus which.
- Sister-in-law of Stella McBride Cyrus.
- Has a nephew Bear Chance Cyrus (b. June 8, 2021) via brother Braison Cyrus and sister-in-law Stella McBride Cyrus.
- Brandi's mother, Tish Cyrus, married actor Dominic Purcell August 19th, 2023. Dominic has 4 children: daughters Audrey and Lily Rose, and sons Joseph and Augustus.
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